HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: STIM1 (Q13586)
Stromal interaction molecule 1
Gene: STIM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35384245, 32814053
Identification Methods	proximity labelling technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 685
+	Hs
		665597 EPHB2_HUMAN (1-788): 0: 624: 19.15		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		665474 EPHA8_HUMAN (1-771): 0: 593: 20.56		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		1040115 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		384799 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		434190 RET_HUMAN (453-801): 9.71e-98: 330: 48.63		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		1081633 NTRK3_HUMAN (130-757): 4.66e-167: 506: 24.59		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		434300 RET_HUMAN (453-801): 9.71e-98: 330: 48.63		STIM2_HUMAN (49-643): 0: 826: 51.93
+	Hs
		729274 VGFR3_HUMAN (7-245): 8.53e-15: 81: 18.22		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		507985 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		STIM1_HUMAN (1-685): 0: 1059: 100.00
+	Hs
		508240 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		STIM2_HUMAN (49-643): 0: 826: 51.93