HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: SCYL2 (Q6P3W7)
SCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa)
Gene: SCYL2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	I-set~Pkinase, PK_Tyr_Ser-Thr~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005794 - Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 806 Hs			1 929
+	Hs
		609219 FGFR3_HUMAN (10-806): 0: 819: 100.00		KS6A3_HUMAN (3-717): 1.11e-135: 425: 12.27
+	Hs
		385016 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		SCYL2_HUMAN (1-929): 0: 699: 99.14
+	Hs
		665243 EPHA2_HUMAN (1-788): 0: 595: 21.50		KS6A2_HUMAN (7-722): 1.93e-133: 419: 12.80
+	Hs
		384892 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		KS6A1_HUMAN (3-717): 3.6e-138: 432: 12.25
+	Hs
		384525 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		KS6A3_HUMAN (3-717): 1.11e-135: 425: 12.27
+	Hs
		385358 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		SCYL1_HUMAN (32-807): 9.42e-131: 414: 17.22
+	Hs
		160396 EPHA2_HUMAN (1-788): 0: 595: 21.50		AURKA_HUMAN (28-326): 7.69e-63: 220: 24.42
+	Hs
		508065 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		SCYL2_HUMAN (1-929): 0: 699: 99.14
+	Hs
		601532 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		SCYL2_HUMAN (1-929): 0: 699: 99.14
+	Hs
		608015 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		SCYL2_HUMAN (1-929): 0: 699: 99.14
+	Hs
		434163 RET_HUMAN (453-801): 9.71e-98: 330: 48.63		KS6A3_HUMAN (3-717): 1.11e-135: 425: 12.27
+	Hs
		508016 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		KS6A1_HUMAN (3-717): 3.6e-138: 432: 12.25
+	Rn
		979772 FGFR1_RAT (1-114): 1.76e-14: 79.7: 18.32		KS6A1_RAT (3-717): 2.4e-137: 429: 11.98
+	Hs
		507919 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		KS6A3_HUMAN (3-717): 1.11e-135: 425: 12.27
+	Hs
		601517 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		KS6A1_HUMAN (3-717): 3.6e-138: 432: 12.25
+	Hs
		607975 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		KS6A1_HUMAN (3-717): 3.6e-138: 432: 12.25
+	Hs
		508015 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		KS6A2_HUMAN (7-722): 1.93e-133: 419: 12.80
+	Hs
		601482 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		KS6A3_HUMAN (3-717): 1.11e-135: 425: 12.27
+	Hs
		607926 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		KS6A3_HUMAN (3-717): 1.11e-135: 425: 12.27
+	Hs
		601516 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		KS6A2_HUMAN (7-722): 1.93e-133: 419: 12.80