HitPredict

Interactor 1: RFX1 (P22670)
MHC class II regulatory factor RFX1 (Enhancer factor C) (EF-C) (Regulatory factor X 1) (RFX) (Transcription factor RFX1)
Gene: RFX1

Interactor 2: NCOA3 (Q9Y6Q9)
Nuclear receptor coactivator 3 (NCoA-3) (EC 2.3.1.48) (ACTR) (Amplified in breast cancer 1 protein) (AIB-1) (CBP-interacting protein) (pCIP) (Class E basic helix-loop-helix protein 42) (bHLHe42) (Receptor-associated coactivator 3) (RAC-3) (Steroid receptor coactivator protein 3) (SRC-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1)
Gene: NCOA3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20181721
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 979 Hs			1 1424
+	Hs
		1210869 RFX6_HUMAN (419-961): 6.07e-127: 409: 29.98		X5DP31_HUMAN (1-569): 1.39e-87: 301: 17.09
+	Hs
		1210863 RFX6_HUMAN (419-961): 6.07e-127: 409: 29.98		ARNT2_HUMAN (1-620): 6.44e-72: 257: 16.69
+	Hs
		1270854 CBP_HUMAN (62-420): 1.89e-09: 64: 13.37		NCOA3_HUMAN (1-1424): 3.11e-164: 533: 100.00
+	Hs
		554312 MUC1_HUMAN (3-324): 1.12e-10: 67.8: 12.95		HIF1A_HUMAN (1-829): 3.49e-114: 381: 14.72
+	Hs
		1085623 CBP_HUMAN (62-420): 1.89e-09: 64: 13.37		HIF1A_HUMAN (1-829): 3.49e-114: 381: 14.72
+	Hs
		1270774 CBP_HUMAN (62-420): 1.89e-09: 64: 13.37		NPAS2_HUMAN (19-807): 7.51e-111: 372: 16.20
+	Rn
		193481 CBP_RAT (2-321): 7.5e-09: 62.1: 13.75		HIF1A_RAT (1-772): 4.57e-109: 367: 14.14
+	Mm
		799605 CBP_MOUSE (73-486): 2.29e-10: 67.1: 10.38		BMAL1_MOUSE (6-541): 2.82e-108: 359: 18.94
+	Hs
		1075384 CBP_HUMAN (62-420): 1.89e-09: 64: 13.37		NCOA2_HUMAN (1-1422): 5.82e-99: 350: 38.89
+	Hs
		126156 CBP_HUMAN (62-420): 1.89e-09: 64: 13.37		BMAL1_HUMAN (6-541): 4.9e-105: 349: 18.23
+	Hs
		1270775 CBP_HUMAN (62-420): 1.89e-09: 64: 13.37		EPAS1_HUMAN (12-878): 3.88e-100: 343: 13.27
+	Mm
		799600 CBP_MOUSE (73-486): 2.29e-10: 67.1: 10.38		BMAL2_MOUSE (27-541): 1.22e-90: 307: 16.58
+	Mm
		101411 F8VPR5_MOUSE (73-486): 2.51e-10: 67.1: 10.38		CLOCK_MOUSE (1-779): 3.86e-79: 282: 13.65
+	Hs
		1078530 CBP_HUMAN (62-420): 1.89e-09: 64: 13.37		NCOA1_HUMAN (1-1353): 9.13e-76: 279: 24.53
+	Hs
		181549 CBP_HUMAN (62-420): 1.89e-09: 64: 13.37		CLOCK_HUMAN (1-791): 2.47e-78: 279: 13.73