HitPredict

Interactor 1: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21203488
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 906 Hs			1 377
+	Hs
		610321 CBL_HUMAN (1-906): 0: 917: 100.00		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		610343 CBL_HUMAN (1-906): 0: 917: 100.00		ACTH_HUMAN (4-377): 0: 597: 98.40
+	Hs
		203220 SYNJ1_HUMAN (542-897): 2.72e-14: 79.6: 10.22		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		554290 MUC1_HUMAN (449-906): 3.82e-14: 79.2: 10.58		ACTA_HUMAN (1-377): 0: 602: 97.88
+	Hs
		932156 MDC1_HUMAN (450-878): 1.89e-11: 70.3: 9.33		ACTC_HUMAN (1-377): 0: 604: 98.94
+	Hs
		891853 SRCAP_HUMAN (395-900): 3.05e-09: 63.4: 10.50		ACTB_HUMAN (5-377): 0: 604: 93.83
+	Hs
		929905 SRCAP_HUMAN (395-900): 3.05e-09: 63.4: 10.50		ACTG_HUMAN (4-377): 0: 604: 93.85
+	Hs
		932219 SRCAP_HUMAN (395-900): 3.05e-09: 63.4: 10.50		ACTC_HUMAN (1-377): 0: 604: 98.94