Protein: CDKN3
Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase)

Gene: CDKN3
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q16667

Gene Ontology (top 5):
GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

667886

CDK2
Cyclin-dependent kinase 2

13

2

Small-scale

0.982

High

443384

CDK1
Cyclin-dependent kinase 1

5

2

Small-scale

0.927

High

1025268

CDK3
Cyclin-dependent kinase 3

2

2

Small-scale

0.747

High

270813

ROCK2
Rho-associated protein kinase 2

1

2

Small-scale

0.724

High

1106270

ROCK1
Rho-associated protein kinase 1

1

2

Small-scale

0.618

High

1161809

MRCKB
Serine/threonine-protein kinase MRCK beta

1

2

Small-scale

0.618

High

1161787

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.586

High

128244

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

0

Small-scale

0.559

High

1161803

RMD5A
E3 ubiquitin-protein transferase RMND5A

2

0

Small-scale

0.559

High

1161798

MS4A3
Membrane-spanning 4-domains subfamily A member 3

1

0

Small-scale

0.529

High

253436

CST8
Cystatin-8

1

0

High-throughput

0.513

High

599596

STMN1
Stathmin

1

0

High-throughput

0.513

High

799162

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.513

High

897539

BPL1
Biotin--protein ligase

1

0

High-throughput

0.513

High

932573

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

0

High-throughput

0.513

High

1088861

TP53B
TP53-binding protein 1

1

0

High-throughput

0.513

High

1104905

XRCC4
DNA repair protein XRCC4

1

0

High-throughput

0.513

High

1161788

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

0

High-throughput

0.513

High

1161791

HORN
Hornerin

1

0

High-throughput

0.513

High

1161792

KIBRA
Protein KIBRA

1

0

High-throughput

0.513

High

1161794

JMY
Junction-mediating and -regulatory protein

1

0

High-throughput

0.513

High

1161797

ARK2N
Protein ARK2N

1

0

High-throughput

0.513

High

1161808

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

0

High-throughput

0.513

High

801337

HSPA9
Stress-70 protein, mitochondrial

1

0

High-throughput

0.493

High

171250

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

Small-scale

0.480

High

610346

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

851334

PRS6B
26S proteasome regulatory subunit 6B

1

2

High-throughput

0.479

High

931531

RD23A
UV excision repair protein RAD23 homolog A

1

2

High-throughput

0.479

High

931669

RD23B
UV excision repair protein RAD23 homolog B

1

1

High-throughput

0.479

High

968717

PRS4
26S proteasome regulatory subunit 4

1

2

High-throughput

0.479

High

975415

PRS10
26S proteasome regulatory subunit 10B

1

2

High-throughput

0.479

High

1161810

NCOA3
Nuclear receptor coactivator 3

1

0

Small-scale

0.460

High

613060

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

765564

BMI1
Polycomb complex protein BMI-1

1

0

Small-scale

0.458

High

856713

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.458

High

884525

SYAC
Alanine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

913332

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.458

High

1032479

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.458

High

1161793

ARG28
Rho guanine nucleotide exchange factor 28

1

0

High-throughput

0.458

High

1161795

IPO4
Importin-4

1

0

High-throughput

0.458

High

1161796

DI3L1
DIS3-like exonuclease 1

1

0

High-throughput

0.458

High

1161799

NP1L4
Nucleosome assembly protein 1-like 4

1

0

High-throughput

0.458

High

1161801

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.458

High

1161802

UN45A
Protein unc-45 homolog A

1

0

High-throughput

0.458

High

1161805

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

0

High-throughput

0.458

High

1161806

ATX10
Ataxin-10

1

0

High-throughput

0.458

High

1064710

CD47
Leukocyte surface antigen CD47

1

0

High-throughput

0.279

Low

1161789

BOP
Protein Bop

1

0

High-throughput

0.279

Low

1161790

R3HCL
Coiled-coil domain-containing protein R3HCC1L

1

0

High-throughput

0.279

Low

1161804

NOL11
Nucleolar protein 11

1

0

High-throughput

0.279

Low

124365

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

522433

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.249

Low

1161800

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.249

Low

1161807

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025