Interactor 1: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: SPY4 (Q9C004)
Protein sprouty homolog 4 (Spry-4)
Gene: SPRY4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.589

The method score is based on:

Property Details
Experiments 18273061
Identification Methods affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation, isothermal titration calorimetry
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005925 - focal adhesion
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 906
Hs

1 299
+ Hs
+ Hs
+ Mm
+ Rn
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024