Protein: PRI2
DNA primase large subunit (DNA primase 58 kDa subunit) (p58)

Gene: PRI2, PRIM2
Organism: Homo sapiens
Interactions: 75
UniProt ID: P49643

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005658 - alpha DNA polymerase:primase complex
GO:0006269 - DNA replication, synthesis of primer
GO:0006270 - DNA replication initiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

830121

PRI1
DNA primase small subunit

5

3

Small-scale

0.928

High

456101

DPOLA
DNA polymerase alpha catalytic subunit

2

3

Small-scale

0.755

High

830165

RAE1L
mRNA export factor RAE1

4

1

High-throughput

0.694

High

830189

MMS19
MMS19 nucleotide excision repair protein homolog

5

0

Small-scale

0.676

High

552222

RFA2
Replication protein A 32 kDa subunit

2

0

Small-scale

0.607

High

830180

P20D2
Xaa-Arg dipeptidase

2

0

High-throughput

0.602

High

282853

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

3

1

Small-scale

0.585

High

830187

RNF31
E3 ubiquitin-protein ligase RNF31

2

1

High-throughput

0.574

High

650661

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

0

Small-scale

0.569

High

283176

RGS20
Regulator of G-protein signaling 20

2

1

High-throughput

0.558

High

830183

NLGNY
Neuroligin-4, Y-linked

2

1

High-throughput

0.558

High

830199

CIA2B
Cytosolic iron-sulfur assembly component 2B

2

0

Small-scale

0.547

High

830172

DCA10
DDB1- and CUL4-associated factor 10

1

1

High-throughput

0.536

High

226852

PRKN
E3 ubiquitin-protein ligase parkin

2

1

High-throughput

0.533

High

149837

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.513

High

380756

S100B
Protein S100-B

1

0

High-throughput

0.513

High

803434

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.513

High

830166

SSRP1
FACT complex subunit SSRP1

1

0

High-throughput

0.513

High

830167

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

830179

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

830181

CDK20
Cyclin-dependent kinase 20

1

0

High-throughput

0.513

High

830192

SHRPN
Sharpin

1

0

High-throughput

0.513

High

830201

AMMR1
Nuclear protein AMMECR1

1

0

High-throughput

0.513

High

830203

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

0

High-throughput

0.513

High

174718

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

1

High-throughput

0.501

High

830170

DPOA2
DNA polymerase alpha subunit B

1

2

Small-scale

0.501

High

830176

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

590718

BTF3
Transcription factor BTF3

1

1

High-throughput

0.489

High

830188

BT3L4
Transcription factor BTF3 homolog 4

1

1

High-throughput

0.489

High

203642

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.486

High

232051

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.486

High

830184

DCA11
DDB1- and CUL4-associated factor 11

1

1

High-throughput

0.479

High

830186

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

830196

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

830174

Q6P9E2
RECK protein

1

1

High-throughput

0.470

High

116797

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.458

High

244111

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

294531

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

346230

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

719961

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

826240

CDK8
Cyclin-dependent kinase 8

1

0

High-throughput

0.458

High

830163

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

830168

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

830171

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

830178

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

830185

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

830194

STN1
CST complex subunit STN1

1

0

High-throughput

0.458

High

328433

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

1

High-throughput

0.439

High

684515

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.437

High

830173

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

830175

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

401637

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

717560

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.426

High

64104

A6NMU8
Neuroligin 4 Y-linked

1

1

High-throughput

0.407

High

72181

B3KSW4
Regulator of G protein signaling 20

1

1

High-throughput

0.407

High

515818

PRPS2
Ribose-phosphate pyrophosphokinase 2

3

0

High-throughput

0.347

High

830198

KLH20
Kelch-like protein 20

3

0

High-throughput

0.347

High

830191

ERP44
Endoplasmic reticulum resident protein 44

2

0

High-throughput

0.328

High

830190

DUS9
Dual specificity protein phosphatase 9

2

0

High-throughput

0.318

High

179157

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

311676

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.279

Low

591282

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

830177

MILR1
Allergin-1

1

0

High-throughput

0.279

Low

830182

BBS1
Bardet-Biedl syndrome 1 protein

1

0

High-throughput

0.279

Low

830197

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.279

Low

830200

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.279

Low

830202

NGN3
Neurogenin-3

1

0

High-throughput

0.279

Low

384486

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

532429

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.249

Low

622564

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.249

Low

830164

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.249

Low

830169

TRI14
Tripartite motif-containing protein 14

1

0

High-throughput

0.249

Low

830193

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

830195

GFOD1
Glucose-fructose oxidoreductase domain-containing protein 1

1

0

High-throughput

0.249

Low

56600

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024