HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: TBB5 (P99024)
Tubulin beta-5 chain
Gene: Tubb5

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27474268
Identification Methods	affinity chromatography technology
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045121 - membrane raft
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 913 Mm			1 444
+	Mm
		610577 CBL_MOUSE (1-913): 0: 923: 100.00		TBB4B_MOUSE (1-427): 0: 707: 98.36
+	Hs
		610390 CBL_HUMAN (1-913): 0: 894: 91.05		TBB3_HUMAN (1-444): 0: 712: 92.57
+	Hs
		428020 CBL_HUMAN (1-913): 0: 894: 91.05		TBB5_HUMAN (1-429): 0: 709: 100.00
+	Hs
		610348 CBL_HUMAN (1-913): 0: 894: 91.05		TBB4B_HUMAN (1-427): 0: 707: 98.36
+	Hs
		610500 CBL_HUMAN (1-913): 0: 894: 91.05		TBB2B_HUMAN (1-430): 0: 707: 97.44
+	Hs
		610394 CBL_HUMAN (1-913): 0: 894: 91.05		TBB2A_HUMAN (1-430): 0: 704: 96.98
+	Hs
		990836 ZO1_HUMAN (435-850): 6.77e-22: 104: 14.39		TBB3_HUMAN (1-444): 0: 712: 92.57
+	Hs
		428157 ZO1_HUMAN (435-850): 6.77e-22: 104: 14.39		TBB5_HUMAN (1-429): 0: 709: 100.00
+	Hs
		381173 ZO1_HUMAN (435-850): 6.77e-22: 104: 14.39		TBB4A_HUMAN (1-427): 0: 702: 97.42