HitPredict

Interactor 1: PAR2 (P55085)
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]
Gene: F2RL1

Interactor 2: TMCO1 (Q9UM00)
Calcium load-activated calcium channel (CLAC channel) (GEL complex subunit TMCO1) (Transmembrane and coiled-coil domain-containing protein 1) (Transmembrane and coiled-coil domains protein 4) (Xenogeneic cross-immune protein PCIA3)
Gene: TMCO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 397 Hs			1 239
+	Hs
		782490 P2RY2_HUMAN (67-394): 2.77e-79: 250: 26.71		TMCO1_HUMAN (1-239): 1.85e-152: 425: 100.00
+	Hs
		849720 CCR6_HUMAN (72-394): 3.15e-79: 250: 23.57		TMCO1_HUMAN (1-239): 1.85e-152: 425: 100.00
+	Hs
		1031116 GPR17_HUMAN (57-367): 8.1e-79: 249: 29.02		TMCO1_HUMAN (1-239): 1.85e-152: 425: 100.00
+	Hs
		1202758 P2RY8_HUMAN (61-395): 1.57e-77: 245: 34.62		TMCO1_HUMAN (1-239): 1.85e-152: 425: 100.00
+	Hs
		723435 APJ_HUMAN (55-383): 7.14e-70: 226: 23.17		TMCO1_HUMAN (1-239): 1.85e-152: 425: 100.00