HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: RIGI (Q6Q899)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	23374343
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 913 Mm			1 926
+	Hs
		321874 CBL_HUMAN (1-913): 0: 894: 91.05		RIGI_HUMAN (1-925): 0: 598: 77.08
+	Mm
		610605 CBL_MOUSE (1-913): 0: 923: 100.00		DDX3X_MOUSE (381-767): 1.05e-33: 140: 12.84
+	Hs
		610467 CBL_HUMAN (1-913): 0: 894: 91.05		DDX17_HUMAN (459-831): 9.96e-40: 159: 14.39
+	Hs
		571308 CBL_HUMAN (1-913): 0: 894: 91.05		DDX5_HUMAN (511-792): 5.62e-37: 150: 17.24
+	Mm
		1163120 KMT2C_MOUSE (417-910): 7.06e-11: 68.8: 10.51		RIGI_MOUSE (1-926): 0: 602: 100.00
+	Mm
		1161034 KMT2D_MOUSE (521-912): 6.7e-09: 62.3: 9.44		RIGI_MOUSE (1-926): 0: 602: 100.00
+	Sc
		624087 SEC31_YEAST (417-756): 8.87e-12: 71.5: 9.86		DBP2_YEAST (459-777): 7.58e-35: 142: 12.89