HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30890647
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Cpn60_TCP1
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044297 - cell body GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 543
+	Hs
		953055 ACTB_HUMAN (4-377): 0: 598: 94.12		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		993309 ACTG_HUMAN (4-377): 0: 598: 94.39		TCPH_HUMAN (1-543): 0: 647: 100.00
+	Hs
		881871 ACTC_HUMAN (1-377): 0: 599: 100.00		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		881853 ACTB_HUMAN (4-377): 0: 598: 94.12		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		881869 ACTG_HUMAN (4-377): 0: 598: 94.39		TCPG_HUMAN (1-541): 0: 577: 31.09
+	Hs
		875909 ACTC_HUMAN (1-377): 0: 599: 100.00		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		875910 ACTS_HUMAN (1-377): 0: 599: 98.94		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		875890 ACTB_HUMAN (4-377): 0: 598: 94.12		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		875907 ACTG_HUMAN (4-377): 0: 598: 94.39		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		875902 ACTA_HUMAN (1-377): 0: 597: 98.41		TCPE_HUMAN (3-527): 0: 557: 29.59
+	Hs
		610612 ACTC_HUMAN (1-377): 0: 599: 100.00		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610594 ACTB_HUMAN (4-377): 0: 598: 94.12		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		610610 ACTG_HUMAN (4-377): 0: 598: 94.39		TCPA_HUMAN (2-533): 0: 544: 34.54
+	Hs
		899338 ACTC_HUMAN (1-377): 0: 599: 100.00		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899339 ACTS_HUMAN (1-377): 0: 599: 98.94		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899318 ACTB_HUMAN (4-377): 0: 598: 94.12		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899336 ACTG_HUMAN (4-377): 0: 598: 94.39		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79
+	Hs
		899329 ACTA_HUMAN (1-377): 0: 597: 98.41		TCPD_HUMAN (24-520): 4.06e-90: 288: 33.79