HitPredict

Interactor 1: BAGP (P22809)
Homeobox protein bagpipe (Homeobox protein NK-3)
Gene: bap

Interactor 2: ABDA (P29555)
Homeobox protein abdominal-A
Gene: abd-A

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.800

Property	Details
Experiments	25869471, 30247122
Identification Methods	affinity chromatography technology, protein complementation assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0043565 - sequence-specific DNA binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 382 Dm			1 590
+	Dm
		668243 AL_DROME (133-371): 1.11e-36: 139: 18.55		ABDA_DROME (1-590): 6.66e-69: 235: 100.00
+	Dm
		611844 BAGP_DROME (1-382): 6.62e-59: 197: 100.00		UBX_DROME (286-464): 7.93e-37: 143: 40.58
+	Dm
		367177 BAGP_DROME (1-382): 6.62e-59: 197: 100.00		ANTP_DROME (300-478): 3.78e-36: 141: 38.17
+	Dm
		447320 BAGP_DROME (1-382): 6.62e-59: 197: 100.00		SCR_DROME (341-456): 2.09e-22: 101: 55.56
+	Dm
		949988 AL_DROME (133-371): 1.11e-36: 139: 18.55		UBX_DROME (286-464): 7.93e-37: 143: 40.58
+	Ce
		712522 Q9XVN4_CAEEL (111-310): 9.95e-37: 135: 22.94		LIN39_CAEEL (288-458): 6.34e-36: 136: 35.03
+	Ce
		712513 Q19937_CAEEL (20-240): 3.06e-36: 132: 27.75		LIN39_CAEEL (288-458): 6.34e-36: 136: 35.03
+	Hs
		201876 ALX4_HUMAN (96-372): 7.21e-33: 128: 16.78		HXA3_HUMAN (244-479): 4.21e-35: 139: 26.72
+	Hs
		678782 HXD3_HUMAN (157-341): 9.11e-35: 134: 27.86		ALX4_HUMAN (195-563): 5.32e-31: 127: 17.11
+	Hs
		174013 NKX25_HUMAN (17-341): 1.13e-36: 137: 27.16		SHOX_HUMAN (387-457): 1.79e-30: 122: 36.62
+	Hs
		1077278 ALX4_HUMAN (96-372): 7.21e-33: 128: 16.78		ALX1_HUMAN (307-544): 5.03e-32: 128: 16.32
+	Hs
		1328470 ALX4_HUMAN (96-372): 7.21e-33: 128: 16.78		ALX4_HUMAN (195-563): 5.32e-31: 127: 17.11
+	Hs
		568043 ALX4_HUMAN (96-372): 7.21e-33: 128: 16.78		HXB6_HUMAN (276-476): 1.12e-32: 127: 36.82
+	Hs
		980974 ALX4_HUMAN (96-372): 7.21e-33: 128: 16.78		EMX1_HUMAN (223-485): 3.39e-32: 127: 21.30
+	Ce
		590580 HM14_CAEEL (170-350): 1.64e-33: 129: 17.99		HM14_CAEEL (393-568): 4.13e-28: 117: 13.07
+	Hs
		446864 HXA5_HUMAN (81-250): 8.18e-34: 128: 25.15		HXD4_HUMAN (272-491): 1.44e-28: 116: 29.55
+	Hs
		658621 MSX1_HUMAN (85-251): 2.11e-37: 138: 32.77		HXC8_HUMAN (393-456): 5.33e-21: 94.4: 76.56
+	Hs
		678775 HXD3_HUMAN (157-341): 9.11e-35: 134: 27.86		HXC8_HUMAN (393-456): 5.33e-21: 94.4: 76.56
+	Hs
		567821 HXA1_HUMAN (76-247): 3.01e-36: 136: 26.70		HXB9_HUMAN (399-455): 6.44e-15: 76.6: 70.18