HitPredict

Interactor 1: FBLN1 (P23142)
Fibulin-1 (FIBL-1)
Gene: FBLN1

Interactor 2: SMAD3 (P84022)
Mothers against decapentaplegic homolog 3 (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (hMAD-3) (JV15-2) (SMAD family member 3) (SMAD 3) (Smad3) (hSMAD3)
Gene: SMAD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21988832
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010628 - positive regulation of gene expression
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 703 Hs			1 425
+	Hs
		804201 NOTC1_HUMAN (360-662): 1.29e-18: 93.1: 15.16		SMAD3_HUMAN (1-425): 0: 636: 100.00
+	Hs
		950260 NOTC4_HUMAN (14-313): 1.76e-09: 63.5: 9.29		SMAD3_HUMAN (1-425): 0: 636: 100.00
+	Hs
		980382 NOTC2_HUMAN (265-642): 2.76e-25: 114: 16.43		SMAD1_HUMAN (1-425): 0: 559: 60.09
+	Hs
		1078639 NOTC4_HUMAN (14-313): 1.76e-09: 63.5: 9.29		SMAD2_HUMAN (1-425): 0: 589: 83.73
+	Hs
		171369 NOTC1_HUMAN (360-662): 1.29e-18: 93.1: 15.16		SMAD9_HUMAN (1-425): 0: 559: 58.62
+	Hs
		612847 FBLN1_HUMAN (1-703): 1.69e-89: 296: 100.00		SMAD4_HUMAN (23-414): 1.55e-117: 355: 33.21
+	Hs
		1035611 TEN3_HUMAN (480-665): 3.23e-12: 72.3: 10.66		SMAD4_HUMAN (23-414): 1.55e-117: 355: 33.21
+	Hs
		1035564 NOTC4_HUMAN (14-313): 1.76e-09: 63.5: 9.29		SMAD4_HUMAN (23-414): 1.55e-117: 355: 33.21