HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: PTBP1 (P26599)
Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I)
Gene: PTBP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 17507659, 10653975, 8449401, 15975576, 11514619
Identification Methods affinity chromatography technology, pull down, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains NOPS~RRM_1, RRM_1~RRM_1, RRM_1~RRM_5
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006397 - mRNA processing
GO:0008380 - RNA splicing
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 707
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024