HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17361185
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 707 Hs			1 248
+	Hs
		909516 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		516374 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		684050 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		613403 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		927003 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37
+	Mm
		910319 SFPQ_MOUSE (230-707): 1.53e-70: 245: 98.95		1433E_MOUSE (2-246): 4.41e-146: 410: 60.41
+	Hs
		516444 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Hs
		909587 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		1433E_HUMAN (2-246): 4.41e-146: 410: 60.41
+	Mm
		910328 NONO_MOUSE (233-707): 2.48e-67: 231: 55.04		1433E_MOUSE (2-246): 4.41e-146: 410: 60.41
+	Mm
		926857 SFPQ_MOUSE (230-707): 1.53e-70: 245: 98.95		1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96
+	Hs
		684206 MINK1_HUMAN (38-194): 2.38e-40: 161: 32.95		1433S_HUMAN (1-248): 3.48e-158: 440: 100.00
+	Hs
		646864 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		683319 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62
+	Hs
		613340 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		613399 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		516440 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		904585 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		904923 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		1433G_HUMAN (1-242): 1.86e-98: 289: 65.16
+	Hs
		647104 MINK1_HUMAN (38-194): 2.38e-40: 161: 32.95		1433T_HUMAN (1-238): 9.98e-108: 312: 71.85
+	Hs
		683539 MINK1_HUMAN (38-194): 2.38e-40: 161: 32.95		1433B_HUMAN (1-239): 3.41e-100: 293: 68.62