HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	37071682, 37207277
Identification Methods	cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 707 Hs			1 2221
+	Hs
		1031322 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		516510 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047086 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1031434 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45
+	Hs
		516654 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45
+	Hs
		1303351 PABP3_HUMAN (287-700): 9.1e-69: 239: 16.88		SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45
+	Dm
		597098 PABP_DROME (296-675): 1.13e-65: 230: 14.32		SCN60_DROME (938-1075): 7.5e-12: 73.6: 27.54
+	Dm
		978471 NONA_DROME (208-658): 1.4e-64: 229: 35.05		SCN60_DROME (938-1075): 7.5e-12: 73.6: 27.54