HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: MEPCE (Q7L2J0)
7SK snRNA methylphosphate capping enzyme (MePCE) (EC 2.1.1.-) (Bicoid-interacting protein 3 homolog) (Bin3 homolog)
Gene: MEPCE

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29845934, 24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 707 Hs			1 689
+	Hs
		1031372 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1119138 PAP1L_HUMAN (287-675): 3.88e-71: 244: 16.33		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		516570 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1069718 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1184333 PABP3_HUMAN (287-700): 9.1e-69: 239: 16.88		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1184232 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1184262 PABP5_HUMAN (244-545): 3.2e-43: 162: 15.34		MEPCE_HUMAN (1-689): 0: 1200: 100.00
+	Hs
		1184294 RBM4B_HUMAN (298-436): 1.27e-40: 154: 27.97		MEPCE_HUMAN (1-689): 0: 1200: 100.00