HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: SRRM2 (Q9UQ35)
Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Gene: SRRM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16159877
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 707 Hs			1 2752
+	Hs
		516749 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		1069826 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		SRRM2_HUMAN (1-2752): 2.88e-178: 615: 100.00
+	Hs
		613557 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		516546 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		1069770 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		CIC_HUMAN (216-2751): 1.9e-62: 240: 8.98
+	Hs
		1127659 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		PRC2B_HUMAN (640-2750): 5.74e-64: 245: 9.36
+	Hs
		1031405 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		820908 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		516609 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		TITIN_HUMAN (26-1299): 8.38e-20: 100: 7.11
+	Hs
		613371 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		1069707 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		NIPBL_HUMAN (333-1474): 1.68e-16: 89.1: 14.39
+	Hs
		613570 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		DIDO1_HUMAN (13-1216): 9.01e-11: 70.1: 10.22
+	Hs
		613628 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		516406 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		516766 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11
+	Hs
		516595 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		KMT2C_HUMAN (1760-2747): 2.06e-09: 65.9: 9.01
+	Hs
		965106 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		965152 PABP3_HUMAN (287-700): 9.1e-69: 239: 16.88		ANK2_HUMAN (1488-2676): 2.26e-09: 65.6: 13.23
+	Hs
		820986 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		PRC2A_HUMAN (8-1230): 6.75e-14: 80.5: 10.65
+	Hs
		1263596 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		PRC2C_HUMAN (1360-2752): 9.55e-11: 70.1: 9.11