HitPredict

Interactor 1: TBG1 (P23258)
Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)
Gene: TUBG1

Interactor 2: MZT1 (Q08AG7)
Mitotic-spindle organizing protein 1 (Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1)
Gene: MZT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	26496610, 28514442, 33961781, 23443559, 20360068
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, cosedimentation through density gradient
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000930 - gamma-tubulin complex GO:0005813 - centrosome GO:0005819 - spindle GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 82
+	At
		750777 TBG2_ARATH (1-450): 0: 718: 75.06		MZT1B_ARATH (20-71): 8.36e-20: 76.7: 48.08
+	At
		750774 TBG1_ARATH (1-450): 0: 714: 74.39		MZT1B_ARATH (20-71): 8.36e-20: 76.7: 48.08
+	At
		750775 TBG2_ARATH (1-450): 0: 718: 75.06		MZT1A_ARATH (20-71): 5.94e-17: 69.4: 46.15
+	Sp
		474423 TBG_SCHPO (1-445): 0: 670: 70.92		MZT1_SCHPO (20-72): 3.3e-18: 72.5: 47.17
+	At
		1122961 TBB2_ARATH (3-436): 2.74e-91: 285: 35.99		MZT1B_ARATH (20-71): 8.36e-20: 76.7: 48.08