HitPredict

Interactor 1: IF5A1 (P23301)
Eukaryotic translation initiation factor 5A-1 (eIF-5A-1) (Hypusine-containing protein HP2) (eIF-4D)
Gene: HYP2

Interactor 2: DHYS (P38791)
Deoxyhypusine synthase (DHS) (EC 2.5.1.46)
Gene: DYS1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.674

Property	Details
Experiments	14675757, 18719252, 37968396
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 157 Sc			1 387
+	Sc
		581107 IF5A2_YEAST (1-157): 1.27e-86: 251: 90.45		DHYS_YEAST (1-387): 0: 673: 100.00
+	Dm
		1325764 IF5A_DROME (1-157): 4.77e-82: 240: 62.66		DHYS_DROME (9-387): 0: 592: 50.78
+	Sp
		293167 IF5A1_SCHPO (1-156): 6.63e-85: 247: 68.79		DHYS_SCHPO (10-377): 0: 573: 56.42
+	Sp
		293168 IF5A2_SCHPO (1-156): 3.66e-84: 246: 68.79		DHYS_SCHPO (10-377): 0: 573: 56.42
+	Hs
		826509 IF5A1_HUMAN (1-155): 9.09e-86: 249: 62.58		DHYS_HUMAN (4-377): 0: 568: 54.81
+	Hs
		826550 IF5A2_HUMAN (4-151): 2.28e-84: 246: 64.19		DHYS_HUMAN (4-377): 0: 568: 54.81
+	Ce
		712318 IF5A1_CAEEL (4-155): 1.1e-74: 221: 57.79		DHYS_CAEEL (11-377): 0: 576: 53.93