HitPredict

Interactor 1: PRP28 (P23394)
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (EC 3.6.4.13) (Helicase CA8)
Gene: PRP28

Interactor 2: PRP8 (P33334)
Pre-mRNA-splicing factor 8
Gene: PRP8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 24231520, 34035302, 16429126
Identification Methods pull down, affinity chromatography technology, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~PROCT, Helicase_C~PROCT
Common GO terms GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
and 3 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 588
Sc

1 2413
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024