Protein: Q9VR61
non-specific serine/threonine protein kinase (EC 2.7.11.1)

Gene: Q9VR61, S6kII
Organism: Drosophila melanogaster
Interactions: 199
UniProt ID: Q9VR61

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004711 - ribosomal protein S6 kinase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

614339

SGG
Protein kinase shaggy

1

20

Small-scale

0.724

High

118631

M9NF14
IGF-II mRNA-binding protein, isoform L

1

8

High-throughput

0.618

High

304373

O76876
Protein sex-lethal

1

12

High-throughput

0.618

High

387002

ACT2
Actin-42A

1

11

High-throughput

0.618

High

467141

CSK2A
Casein kinase II subunit alpha

1

15

High-throughput

0.618

High

467202

CSK2B
Casein kinase II subunit beta

1

8

Small-scale

0.618

High

561606

SPTCA
Spectrin alpha chain

1

6

High-throughput

0.618

High

1064248

SQD
RNA-binding protein squid

1

13

High-throughput

0.618

High

1069824

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

4

High-throughput

0.618

High

1265651

Q7K3D4
peptidylprolyl isomerase

1

12

High-throughput

0.618

High

1269978

Q7KV89
Mitogen-activated protein kinase kinase kinase kinase

1

19

High-throughput

0.618

High

1463385

Q9V3E7
LD24793p

1

9

High-throughput

0.618

High

1474149

Q9VFV9
DnaJ-like-2, isoform A

1

8

High-throughput

0.618

High

1476133

Q9VHC7
FI21236p1

1

9

High-throughput

0.618

High

1484682

Q9VYW4
ATP-binding cassette sub-family F member 1

1

1

High-throughput

0.618

High

1484700

DDB1
DNA damage-binding protein 1

1

4

High-throughput

0.618

High

1470156

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

0

High-throughput

0.586

High

462193

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

15

High-throughput

0.553

High

1044935

NONA
Protein no-on-transient A

1

10

High-throughput

0.553

High

1171703

Q24007
Gp150 protein

1

3

High-throughput

0.553

High

1263901

Q7K012
Brahma associated protein 55kD

1

12

High-throughput

0.553

High

1464679

Q9V3W7
LD40489p

1

13

High-throughput

0.553

High

1484665

Q9VS57
RE14391p

1

1

High-throughput

0.553

High

1484666

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

9

High-throughput

0.553

High

1484669

Q9VT19
RRM domain-containing protein

1

10

High-throughput

0.553

High

1484688

Q9W124
LD27920p

1

5

High-throughput

0.553

High

1484686

Q9W0A8
FI01658p

2

1

High-throughput

0.548

High

1484607

MXT
Eukaryotic translation initiation factor 4E-binding protein Mextli

1

0

High-throughput

0.486

High

1303801

Q8INF6
Hexamethylene bisacetamide inducible, isoform B

1

1

High-throughput

0.481

High

1470641

Q9VCQ7
LD40758p

1

5

High-throughput

0.481

High

56743

A1ZAH8
40S ribosomal protein S15

1

1

High-throughput

0.479

High

57305

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

7

High-throughput

0.479

High

68146

A8DY67
Acetyl-CoA carboxylase, isoform E

1

9

High-throughput

0.479

High

95051

E1JH23
Oxysterol-binding protein

1

1

High-throughput

0.479

High

120247

M9PD08
Eukaryotic translation release factor 3, isoform C

1

3

High-throughput

0.479

High

120384

M9PD17
Gigas, isoform B

1

3

High-throughput

0.479

High

120885

M9PEE1
Smallminded, isoform H

1

10

High-throughput

0.479

High

122119

M9PHL6
Bifocal, isoform E

1

1

High-throughput

0.479

High

198185

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

262637

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

356898

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

3

High-throughput

0.479

High

476485

TBB3
Tubulin beta-3 chain

1

20

High-throughput

0.479

High

554101

TCPA
T-complex protein 1 subunit alpha

1

19

High-throughput

0.479

High

618797

DDX17
ATP-dependent RNA helicase p62

1

7

High-throughput

0.479

High

633081

NCD
Protein claret segregational

1

1

High-throughput

0.479

High

674053

BRM
ATP-dependent helicase brm

1

5

High-throughput

0.479

High

715380

BIP
Endoplasmic reticulum chaperone BiP

1

17

High-throughput

0.479

High

760400

TTF2
Transcription termination factor 2

1

1

High-throughput

0.479

High

773390

RFC1
Replication factor C subunit 1

1

5

High-throughput

0.479

High

885137

RL36
Large ribosomal subunit protein eL36

1

2

High-throughput

0.479

High

939578

RS9
Small ribosomal subunit protein uS4

1

1

High-throughput

0.479

High

1019934

1433E
14-3-3 protein epsilon

1

11

High-throughput

0.479

High

1038060

HTS
Protein hu-li tai shao

1

2

High-throughput

0.479

High

1038255

IF4A
Eukaryotic initiation factor 4A

1

14

High-throughput

0.479

High

1070029

RS11
Small ribosomal subunit protein uS17

1

1

High-throughput

0.479

High

1172908

RS5A
Small ribosomal subunit protein uS7A

1

2

High-throughput

0.479

High

1176875

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit 2

1

7

High-throughput

0.479

High

1262243

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

3

High-throughput

0.479

High

1264480

BOP1
Ribosome biogenesis protein BOP1 homolog

1

3

High-throughput

0.479

High

1267277

Q7KKI0
T-complex protein 1 subunit epsilon

1

19

High-throughput

0.479

High

1267365

Q7KLW9
Pre-mRNA-processing factor 19

1

3

High-throughput

0.479

High

1269429

Q7KTV5
Nopp140, isoform B

1

6

High-throughput

0.479

High

1321384

Q8MST5
Tubulin beta chain

1

20

High-throughput

0.479

High

1374493

HDAC1
Histone deacetylase HDAC1

1

9

High-throughput

0.479

High

1378499

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

6

High-throughput

0.479

High

1445536

FMR1
Fragile X messenger ribonucleoprotein 1 homolog

1

1

High-throughput

0.479

High

1458181

EIF3H
Eukaryotic translation initiation factor 3 subunit H

1

6

High-throughput

0.479

High

1463432

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.479

High

1463940

RUVB2
RuvB-like helicase 2

1

4

High-throughput

0.479

High

1464996

Q9V426
LD07162p

1

3

High-throughput

0.479

High

1465474

Q9V455
Importin subunit alpha

1

5

High-throughput

0.479

High

1467758

Q9VAC4
GEO09167p1

1

4

High-throughput

0.479

High

1468541

LARP
La-related protein 1

1

6

High-throughput

0.479

High

1469791

Q9VBX3
Vig2, isoform B

1

3

High-throughput

0.479

High

1470239

Q9VCC9
LD23779p

1

19

High-throughput

0.479

High

1470489

EI3D1
Eukaryotic translation initiation factor 3 subunit D-1

1

1

High-throughput

0.479

High

1473439

Q9VF03
Brahma associated protein 155 kDa

1

3

High-throughput

0.479

High

1474990

IPO9
Importin-9

1

12

High-throughput

0.479

High

1475436

RUVB1
RuvB-like helicase 1

1

4

High-throughput

0.479

High

1477449

NOC2L
Nucleolar complex protein 2

1

1

High-throughput

0.479

High

1477467

DDX47
ATP-dependent RNA helicase DDX47

1

8

High-throughput

0.479

High

1477961

Q9VJ12
Acinus, isoform A

1

1

High-throughput

0.479

High

1478220

Q9VJ74
Probable ATP-dependent RNA helicase DDX23

1

10

High-throughput

0.479

High

1478243

Q9VJ86
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

1480685

Q9VLC5
aldehyde dehydrogenase

1

1

High-throughput

0.479

High

1482299

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

15

High-throughput

0.479

High

1483339

Q9VPL9
FI24801p1

1

3

High-throughput

0.479

High

1484401

Q9VQR9
PAT complex subunit CCDC47

1

1

High-throughput

0.479

High

1484673

AGO2
Protein argonaute-2

1

1

High-throughput

0.479

High

1484674

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

4

High-throughput

0.479

High

1484679

Q9VWL9
LD25711p

1

2

High-throughput

0.479

High

1484692

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

1

High-throughput

0.479

High

1484695

Q9W392
T-complex protein 1 subunit beta

1

17

High-throughput

0.479

High

1174573

EXO1
Exonuclease 1

1

2

High-throughput

0.464

High

54634

A1Z8U0
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

1345673

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.458

High

1465596

Y9776
Zinc finger matrin-type protein CG9776

1

0

High-throughput

0.458

High

1467289

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.458

High

1473905

Q9VFH2
Hexamethylene bisacetamide inducible, isoform A

1

1

High-throughput

0.457

High

94923

E1JGL8
Uncharacterized protein, isoform C

1

5

High-throughput

0.437

High

145789

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

4

High-throughput

0.437

High

232154

O44434
QKR58E-3

1

1

High-throughput

0.437

High

304441

PKHF1
Pleckstrin homology domain-containing family F member 1 homolog

1

2

High-throughput

0.437

High

305442

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

1

High-throughput

0.437

High

471508

RLA1
Large ribosomal subunit protein P1

1

2

High-throughput

0.437

High

479635

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.437

High

607510

RS17
Small ribosomal subunit protein eS17

1

2

High-throughput

0.437

High

627450

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

2

High-throughput

0.437

High

710958

RS6
Small ribosomal subunit protein eS6

1

10

High-throughput

0.437

High

732238

RL7
Large ribosomal subunit protein uL30

1

4

High-throughput

0.437

High

782976

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.437

High

831765

RS4
Small ribosomal subunit protein eS4

1

1

High-throughput

0.437

High

832268

RL13
Large ribosomal subunit protein eL13

1

1

High-throughput

0.437

High

856482

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.437

High

870553

RS15A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

874404

RS25
Small ribosomal subunit protein eS25

1

1

High-throughput

0.437

High

898306

RL9
Large ribosomal subunit protein uL6

1

2

High-throughput

0.437

High

939004

RL14
Large ribosomal subunit protein eL14

1

1

High-throughput

0.437

High

1019464

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

1

High-throughput

0.437

High

1052811

T2FA
General transcription factor IIF subunit 1

1

2

High-throughput

0.437

High

1175618

CAF1
Chromatin assembly factor 1 p55 subunit

1

7

High-throughput

0.437

High

1193034

Q494K2
Chromosome transmission fidelity 4

1

8

High-throughput

0.437

High

1216852

Q5U156
RE01954p

1

3

High-throughput

0.437

High

1269946

Q7KV70
Karst, isoform C

1

6

High-throughput

0.437

High

1270167

Q7KVW1
RE73736p

1

3

High-throughput

0.437

High

1304063

SLE
Protein slender lobes

1

3

High-throughput

0.437

High

1306048

CLSPN
Claspin

1

3

High-throughput

0.437

High

1343655

Q8SX89
Kugelkern, isoform A

1

1

High-throughput

0.437

High

1344559

Q8SYL1
Glutamate-rich WD repeat-containing protein 1

1

6

High-throughput

0.437

High

1377297

Q95RE4
LD37574p

1

6

High-throughput

0.437

High

1409394

Q9BIW6
Brahma-associated protein 111kD

1

2

Small-scale

0.437

High

1458035

SRPRA
Signal recognition particle receptor subunit alpha homolog

1

2

High-throughput

0.437

High

1465527

SPT5H
Transcription elongation factor SPT5

1

6

High-throughput

0.437

High

1466034

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.437

High

1466577

EPB41
Protein 4.1 homolog

1

7

High-throughput

0.437

High

1467107

Q9V9W2
Large ribosomal subunit protein eL6

1

1

High-throughput

0.437

High

1467379

Q9VA69
procollagen-proline 4-dioxygenase

1

1

High-throughput

0.437

High

1467544

RS7
Small ribosomal subunit protein eS7

1

2

High-throughput

0.437

High

1469348

Q9VBN5
60S ribosomal protein L27

1

1

High-throughput

0.437

High

1472783

Q9VEH0
Aluminum tubes, isoform A

1

20

High-throughput

0.437

High

1472851

Q9VEJ1
Branchpoint-bridging protein

1

2

High-throughput

0.437

High

1478249

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

2

High-throughput

0.437

High

1479223

Q9VK59
LD23647p

1

5

High-throughput

0.437

High

1480782

Q9VLK1
U3 small nucleolar ribonucleoprotein protein MPP10

1

1

High-throughput

0.437

High

1480791

Y3096
Ribosomal L1 domain-containing protein CG13096

1

8

High-throughput

0.437

High

1481004

TCP4
RNA polymerase II transcriptional coactivator

1

1

High-throughput

0.437

High

1483110

Q9VP57
LD15904p

1

3

High-throughput

0.437

High

1484298

Q9VQK7
LD45152p

1

1

High-throughput

0.437

High

1484664

RL18
Large ribosomal subunit protein eL18

1

2

High-throughput

0.437

High

1484667

Q9VSR5
GM03767p

1

1

High-throughput

0.437

High

1484670

R10AB
Large ribosomal subunit protein uL1

1

4

High-throughput

0.437

High

1484671

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.437

High

1484675

Q9VV52
LD37257p

1

11

High-throughput

0.437

High

1484676

Q9VV75
AT02348p

1

2

High-throughput

0.437

High

1484677

LUC7L
Putative RNA-binding protein Alsin2

1

2

High-throughput

0.437

High

1484678

Q9VVU2
GEO07453p1

1

1

High-throughput

0.437

High

1484680

Q9VWS3
Rab11 interacting protein, isoform A

1

14

High-throughput

0.437

High

1484684

BRX1
Ribosome biogenesis protein BRX1 homolog

1

1

High-throughput

0.437

High

1484687

Q9W0R0
Cell division cycle 5, isoform A

1

2

High-throughput

0.437

High

1484689

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

High-throughput

0.437

High

1484690

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.437

High

1484691

RTF1
RNA polymerase-associated protein Rtf1

1

1

High-throughput

0.437

High

1484694

Q9W384
Brahma associated protein 111kD

1

1

Small-scale

0.437

High

1484696

RL17
Large ribosomal subunit protein uL22

1

4

High-throughput

0.437

High

1484697

Q9W425
Rabconnectin-3A

1

5

High-throughput

0.437

High

1484699

Q9W4C1
IP13321p

1

1

High-throughput

0.437

High

1484701

X2JE07
Uncharacterized protein, isoform D

1

2

High-throughput

0.437

High

1484698

Q9W499
Large ribosomal subunit protein uL29

2

0

High-throughput

0.313

High

1479795

Q9VKT8
Lipase

1

0

High-throughput

0.265

Low

1484672

Q9VUI0
CG5272 protein

1

0

High-throughput

0.265

Low

61235

A2VEJ9
IP17766p

1

0

High-throughput

0.249

Low

68777

A8JQW3
Pinin, isoform B

1

0

High-throughput

0.249

Low

98456

F0JAG2
MIP27703p

1

0

High-throughput

0.249

Low

196091

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.249

Low

231870

DKC1
H/ACA ribonucleoprotein complex subunit 4

1

0

High-throughput

0.249

Low

235142

O46307
EG:8D8.4 protein

1

0

High-throughput

0.249

Low

263414

PENG
Protein penguin

1

0

High-throughput

0.249

Low

832200

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.249

Low

836570

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.249

Low

1265007

ARC1
Activity-regulated cytoskeleton associated protein 1

1

0

High-throughput

0.249

Low

1269360

Q7KTL4
Septin interacting protein 2, isoform C

1

0

High-throughput

0.249

Low

1273661

NIPB
Nipped-B protein

1

0

High-throughput

0.249

Low

1275272

Y7065
Uncharacterized protein CG7065

1

0

High-throughput

0.249

Low

1286002

Q86MQ9
LD14261p

1

0

High-throughput

0.249

Low

1302247

Q8I937
Ribosome biogenesis regulatory protein

1

0

High-throughput

0.249

Low

1305873

Q8IR21
GH03748p2

1

0

High-throughput

0.249

Low

1321633

GNL3
Guanine nucleotide-binding protein-like 3 homolog

1

0

High-throughput

0.249

Low

1465816

Q9V4D4
TBP-associated factor 3

1

0

High-throughput

0.249

Low

1467204

EBP2
Probable rRNA-processing protein EBP2 homolog

1

0

High-throughput

0.249

Low

1471501

PPAN
Protein Peter pan

1

0

High-throughput

0.249

Low

1472567

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.249

Low

1473786

RRP15
RRP15-like protein

1

0

High-throughput

0.249

Low

1482554

Q9VNB9
Large ribosomal subunit protein eL33

1

0

High-throughput

0.249

Low

1482666

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.249

Low

1484668

Q9VSY2
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.249

Low

1484681

RRP12
RRP12-like protein

1

0

High-throughput

0.249

Low

1484683

Q9VZC8
GEO12024p1

1

0

High-throughput

0.249

Low

1484685

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.249

Low

1484693

DCAF1
Protein mahjong

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025