HitPredict

Interactor 1: PP4C (A6H772)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16)
Gene: PPP4C

Interactor 2: F1MRS1 (F1MRS1)
Protein phosphatase 4 regulatory subunit 1
Gene: PPP4R1

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	10026142
Identification Methods	chromatography technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HEAT~Metallophos
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 307 Bt			1 945
+	Hs
		890987 PP4C_HUMAN (1-307): 0: 536: 100.00		PP4R1_HUMAN (27-945): 0: 927: 83.53
+	Hs
		915244 PP2AB_HUMAN (6-307): 0: 523: 65.23		PP4R1_HUMAN (27-945): 0: 927: 83.53
+	Hs
		930933 PP2AA_HUMAN (6-307): 0: 522: 65.89		PP4R1_HUMAN (27-945): 0: 927: 83.53
+	Hs
		672060 PP4C_HUMAN (1-307): 0: 536: 100.00		2AAA_HUMAN (233-803): 2.99e-32: 135: 13.49
+	Hs
		672395 PP4C_HUMAN (1-307): 0: 536: 100.00		2AAB_HUMAN (233-804): 4.26e-31: 131: 14.26
+	Hs
		87319 PP2AB_HUMAN (6-307): 0: 523: 65.23		C9J9C1_HUMAN (236-803): 1.62e-32: 136: 13.56
+	Hs
		672072 PP2AB_HUMAN (6-307): 0: 523: 65.23		2AAA_HUMAN (233-803): 2.99e-32: 135: 13.49
+	Hs
		87320 PP2AA_HUMAN (6-307): 0: 522: 65.89		C9J9C1_HUMAN (236-803): 1.62e-32: 136: 13.56
+	Mm
		915332 PP2AB_MOUSE (6-307): 0: 523: 65.23		2AAA_MOUSE (233-803): 3.24e-32: 135: 13.49
+	Hs
		672079 PP2AA_HUMAN (6-307): 0: 522: 65.89		2AAA_HUMAN (233-803): 2.99e-32: 135: 13.49
+	Mm
		930638 PP2AA_MOUSE (6-307): 0: 522: 65.89		2AAA_MOUSE (233-803): 3.24e-32: 135: 13.49
+	Hs
		672399 PP2AB_HUMAN (6-307): 0: 523: 65.23		2AAB_HUMAN (233-804): 4.26e-31: 131: 14.26
+	Hs
		672402 PP2AA_HUMAN (6-307): 0: 522: 65.89		2AAB_HUMAN (233-804): 4.26e-31: 131: 14.26
+	Dm
		619857 PP2A_DROME (2-307): 0: 522: 64.05		2AAA_DROME (233-779): 8.33e-21: 99.6: 12.57
+	Hs
		890979 PP4C_HUMAN (1-307): 0: 536: 100.00		PP4R4_HUMAN (51-365): 1.14e-09: 64.5: 18.10
+	Mm
		956531 PP4C_MOUSE (1-307): 0: 536: 100.00		PP4R4_MOUSE (51-365): 3.18e-09: 63: 17.29
+	Sp
		619320 PP2A2_SCHPO (2-307): 0: 507: 63.40		2AAA_SCHPO (616-921): 4.04e-18: 91.1: 16.51
+	Sp
		619310 PP2A1_SCHPO (2-307): 3.56e-154: 435: 63.19		2AAA_SCHPO (616-921): 4.04e-18: 91.1: 16.51
+	Sc
		618757 PP2A1_YEAST (4-307): 1.5e-148: 423: 60.98		2AAA_YEAST (19-366): 2.8e-15: 82.2: 14.89
+	Hs
		135476 PPP6_HUMAN (6-307): 1.53e-148: 420: 61.92		GCN1_HUMAN (13-925): 3.11e-13: 76.5: 12.56