HitPredict

Interactor 1: KS6B1 (P23443)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: RPS6KB1

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.799

The method score is based on:

Property Details
Experiments 15149849, 35271311, 11438723
Identification Methods biochemical, anti tag coimmunoprecipitation, beta lactamase complementation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~Pkinase, Pkinase~Pkinase, Pkinase~Pkinase_C
Common GO terms GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0004712 - protein serine/threonine/tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 14 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 525
Hs

1 480
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Last updated: 15 Jul 2024