Protein: Q9V455
Importin subunit alpha

Gene: Q9V455, Kap-alpha3
Organism: Drosophila melanogaster
Interactions: 169
UniProt ID: Q9V455

Gene Ontology (top 5):
GO:0005112 - Notch binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006606 - protein import into nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

197653

IMB
Importin subunit beta

3

20

Small-scale

0.817

High

911473

IMA
Importin subunit alpha

2

8

High-throughput

0.737

High

1465452

IPO9
Importin-9

2

20

High-throughput

0.737

High

1465468

Q9VN44
FI07923p

2

20

High-throughput

0.737

High

451828

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

1

Small-scale

0.713

High

1174514

HMG2
High mobility group protein DSP1

1

7

High-throughput

0.656

High

1465466

DSF
Protein dissatisfaction

1

12

High-throughput

0.656

High

624372

CI
Transcriptional activator cubitus interruptus

2

7

Small-scale

0.636

High

1465444

Q9VC93
Exosome complex exonuclease RRP44

2

2

Small-scale

0.584

High

1264033

NUP50
Nuclear pore complex protein Nup50

1

20

High-throughput

0.575

High

1457441

XPO1
Exportin-1

1

9

High-throughput

0.575

High

565013

ATNA
Sodium/potassium-transporting ATPase subunit alpha

2

1

High-throughput

0.571

High

704377

SYEP
Bifunctional glutamate/proline--tRNA ligase

2

1

High-throughput

0.571

High

782757

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

2

3

High-throughput

0.571

High

1346261

Q8T8W3
AT21416p

2

2

High-throughput

0.571

High

1465471

Q9VQL1
serine--tRNA ligase

2

3

High-throughput

0.571

High

1465476

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

1

High-throughput

0.571

High

1465461

NFS1
Cysteine desulfurase, mitochondrial

2

0

High-throughput

0.547

High

1465499

Q9VZL3
very-long-chain enoyl-CoA reductase

2

0

High-throughput

0.547

High

197084

O18332
FI01544p

1

0

High-throughput

0.546

High

1070691

Q0KHU0
Myosin 10A, isoform D

1

0

Small-scale

0.529

High

1465484

NKD
Protein naked cuticle

1

0

Small-scale

0.529

High

715136

CLH
Clathrin heavy chain

2

1

High-throughput

0.521

High

852207

COPB
Coatomer subunit beta

2

1

High-throughput

0.521

High

875260

TCPG
T-complex protein 1 subunit gamma

2

1

High-throughput

0.521

High

1173563

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

2

1

High-throughput

0.521

High

1264522

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

1

High-throughput

0.521

High

1265812

Q7K3J0
T-complex protein 1 subunit theta

2

1

High-throughput

0.521

High

1465435

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

2

3

High-throughput

0.521

High

1465438

Q9V9Q4
LD43819p

2

1

High-throughput

0.521

High

1465440

Q9VAL7
Calnexin 99A, isoform A

2

1

High-throughput

0.521

High

1465443

Q9VBU5
3-dehydrosphinganine reductase

2

1

High-throughput

0.521

High

1465453

Q9VHL2
T-complex protein 1 subunit eta

2

1

High-throughput

0.521

High

1465486

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

2

1

High-throughput

0.521

High

1465488

Q9VWL0
Mec2

2

5

High-throughput

0.521

High

1465506

Q9W3N1
RH59310p

2

2

High-throughput

0.521

High

232116

ESS2
Splicing factor ESS-2 homolog

1

1

High-throughput

0.508

High

304566

ARI2
Potential E3 ubiquitin-protein ligase ariadne-2

1

1

High-throughput

0.508

High

633104

CNC
Segmentation protein cap'n'collar

1

8

High-throughput

0.508

High

1379132

TIP60
Histone acetyltransferase Tip60

1

7

High-throughput

0.508

High

1465451

Q9VGL0
LD43047p

1

20

High-throughput

0.508

High

1265683

Q7K3E9
LD32860p

1

0

High-throughput

0.486

High

1465495

Q9VYY8
sphingosine kinase

1

0

High-throughput

0.486

High

1465511

FL2D
Pre-mRNA-splicing regulator female-lethal(2)D

1

0

High-throughput

0.486

High

117669

L0MPR7
Twin of eyeless, isoform C

1

1

High-throughput

0.481

High

120082

M9PCA3
LIM homeobox transcription factor 1 alpha, isoform C

1

2

High-throughput

0.481

High

683707

DPOLA
DNA polymerase alpha catalytic subunit

1

2

Small-scale

0.481

High

1465489

Q9VXG5
TNF-receptor-associated factor-like, isoform B

1

2

High-throughput

0.481

High

355862

O96660
Mothers against decapentaplegic homolog

1

1

Small-scale

0.479

High

1172642

SIMA
Protein similar

1

13

High-throughput

0.479

High

1303708

AKT1
RAC serine/threonine-protein kinase

1

4

High-throughput

0.479

High

1375016

Q94533
Ribosomal protein S6 kinase

1

4

High-throughput

0.479

High

1465436

ANLN
Anillin

1

5

Small-scale

0.479

High

1465437

CID
Histone H3-like centromeric protein cid

1

8

Small-scale

0.479

High

1465474

Q9VR61
non-specific serine/threonine protein kinase

1

5

High-throughput

0.479

High

1465505

Q9W392
T-complex protein 1 subunit beta

1

2

High-throughput

0.479

High

1465450

Q9VF13
Uncharacterized protein, isoform C

1

3

High-throughput

0.464

High

1465493

Q9VXS4
Uncharacterized protein, isoform A

1

1

High-throughput

0.464

High

717031

SCAL
Protein scalloped

1

0

Small-scale

0.458

High

1465462

PIWI
Protein piwi

1

0

Small-scale

0.458

High

1378977

Q960H6
LP08566p

1

2

High-throughput

0.457

High

1465475

AKIRN
Akirin

1

3

Small-scale

0.457

High

1465478

Q9VTW5
LIM homeobox transcription factor 1 alpha, isoform B

1

2

High-throughput

0.457

High

1465510

Q9XZC2
Transcription factor Toy

1

1

High-throughput

0.457

High

58099

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.445

High

198070

PRS8
26S proteasome regulatory subunit 8

1

5

High-throughput

0.445

High

356826

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

20

High-throughput

0.445

High

875000

PRS4
26S proteasome regulatory subunit 4

1

5

High-throughput

0.445

High

911759

POLO
Serine/threonine-protein kinase polo

1

4

High-throughput

0.445

High

1057345

ARL2
ADP-ribosylation factor-like protein 2

1

2

High-throughput

0.445

High

1069752

Q0E931
GTP-binding protein 1

1

1

High-throughput

0.445

High

1173935

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

20

High-throughput

0.445

High

1176005

MCM4
DNA replication licensing factor MCM4

1

6

High-throughput

0.445

High

1267706

Q7KMQ0
26S proteasome regulatory subunit 7

1

5

High-throughput

0.445

High

1268036

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

4

High-throughput

0.445

High

1305247

Q8IQ97
Pebble, isoform B

1

5

High-throughput

0.445

High

1463881

SEC13
Protein SEC13 homolog

1

4

High-throughput

0.445

High

1464424

Q9V3V6
26S proteasome regulatory complex subunit p50

1

7

High-throughput

0.445

High

1464849

Q9V405
26S proteasome regulatory subunit 6B

1

4

High-throughput

0.445

High

1465166

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

1465454

ARL8
ADP-ribosylation factor-like protein 8

1

2

High-throughput

0.445

High

1465455

Q9VI53
LD44267p

1

5

High-throughput

0.445

High

1465456

DDX47
ATP-dependent RNA helicase DDX47

1

3

High-throughput

0.445

High

1465464

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

7

High-throughput

0.445

High

1465480

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.445

High

1465490

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

1465494

RENT1
Regulator of nonsense transcripts 1 homolog

1

3

High-throughput

0.445

High

1465496

Q9VZ88
AT07585p

1

5

High-throughput

0.445

High

1465507

Q9W414
Regulatory particle triple-A ATPase 4

1

5

High-throughput

0.445

High

1465512

SYQ
Probable glutamine--tRNA ligase

1

1

High-throughput

0.445

High

52686

A1Z729
NADP-retinol dehydrogenase

1

2

High-throughput

0.437

High

1011981

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

1

2

High-throughput

0.437

High

1260758

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.437

High

1269242

Q7KTD0
ABC-type glutathione-S-conjugate transporter

1

3

High-throughput

0.437

High

1465442

Q9VAY2
Heat shock protein 83

1

2

High-throughput

0.437

High

1465513

Q9Y162
vesicle-fusing ATPase

1

5

High-throughput

0.437

High

437998

PYR1
Multifunctional protein r

1

0

High-throughput

0.426

High

669717

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.426

High

829661

ARF4
ADP ribosylation factor 4

1

0

High-throughput

0.426

High

1059165

ROP
Protein ROP

1

0

High-throughput

0.426

High

1321442

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

1344232

Q8SY53
GH11935p

1

0

High-throughput

0.426

High

1375209

Q94883
DNA replication-related element factor, isoform A

1

0

High-throughput

0.426

High

1465116

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.426

High

1465441

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

0

High-throughput

0.426

High

1465449

Q9VEP0
Regulatory protein zeste

1

0

High-throughput

0.426

High

1465485

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.426

High

1465501

Q9W0E4
Aminopeptidase

1

0

High-throughput

0.426

High

53693

A1Z843
Nodal modulator 3

1

1

High-throughput

0.407

High

55802

A1Z9K0
Uncharacterized protein, isoform B

1

3

High-throughput

0.407

High

652077

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

1

High-throughput

0.407

High

852957

ACTZ
Actin-related protein 1

1

6

High-throughput

0.407

High

1070101

Q0E9E2
Pyruvate carboxylase

1

1

High-throughput

0.407

High

1234109

SARM1
NAD(+) hydrolase sarm1

1

4

High-throughput

0.407

High

1236878

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

1

High-throughput

0.407

High

1263219

Q7JXU4
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.407

High

1268710

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

2

High-throughput

0.407

High

1344111

Q8SY39
ATP-dependent RNA helicase DDX54

1

3

High-throughput

0.407

High

1378467

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

3

High-throughput

0.407

High

1378628

Q95WY3
Nucleolar protein 56

1

14

High-throughput

0.407

High

1378824

Q960C7
NADP-retinol dehydrogenase

1

2

High-throughput

0.407

High

1465446

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

6

High-throughput

0.407

High

1465448

Q9VEH0
Aluminum tubes, isoform A

1

3

High-throughput

0.407

High

1465459

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

3

High-throughput

0.407

High

1465460

Q9VKC8
FI03495p

1

8

High-throughput

0.407

High

1465463

Q9VKU1
long-chain-fatty-acid--CoA ligase

1

2

High-throughput

0.407

High

1465472

Q9VQL7
Fatty acid synthase

1

1

High-throughput

0.407

High

1465492

Q9VXR5
ATP-binding cassette sub-family F member 2

1

2

High-throughput

0.407

High

1465508

Q9W4N8
LD30122p

1

2

High-throughput

0.407

High

55457

A1Z9E3
Elongation factor Tu

2

0

High-throughput

0.298

High

1268170

Q7KN94
Electron transfer flavoprotein subunit alpha

2

0

High-throughput

0.298

High

1343138

Q8STG9
DSec61alpha

2

0

High-throughput

0.298

High

1465363

KRH2
Krueppel homolog 2

2

0

High-throughput

0.298

High

1465457

Q9VJD1
Glucosidase 2 subunit beta

2

0

High-throughput

0.298

High

1465482

Q9VV75
AT02348p

2

0

High-throughput

0.298

High

1465491

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

0

High-throughput

0.298

High

1465470

Q9VQI5
Interferon-related developmental regulator 1

2

0

High-throughput

0.288

High

1465467

Q9VML8
GH01721p

1

0

High-throughput

0.282

High

1465497

Q9VZ90
Uncharacterized protein

1

0

High-throughput

0.265

Low

1465498

Q9VZF0
LD44732p

1

0

High-throughput

0.265

Low

1465445

Q9VCQ7
LD40758p

1

0

High-throughput

0.251

Low

1069179

Q0E8E8
Phosphate carrier protein, mitochondrial

1

0

High-throughput

0.249

Low

1465487

Q9VWJ6
FI03615p

1

0

High-throughput

0.249

Low

1465503

GALE
UDP-glucose 4-epimerase

1

0

High-throughput

0.249

Low

53149

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

144889

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.232

Low

263394

PENG
Protein penguin

1

0

High-throughput

0.232

Low

304239

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.232

Low

360563

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

834864

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.232

Low

1237019

Q6NP72
GEO09659p1

1

0

High-throughput

0.232

Low

1266265

Q7K485
Cathepsin D

1

0

High-throughput

0.232

Low

1268346

DYM
Dymeclin

1

0

High-throughput

0.232

Low

1346052

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

0

High-throughput

0.232

Low

1376850

LDH
L-lactate dehydrogenase

1

0

High-throughput

0.232

Low

1465439

Q9VAH7
N-terminal kinase-like protein

1

0

High-throughput

0.232

Low

1465447

Q9VDK7
Signal recognition particle subunit SRP72

1

0

High-throughput

0.232

Low

1465458

Q9VK46
Protein YIPF

1

0

High-throughput

0.232

Low

1465465

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

1465469

NUBP2
Cytosolic Fe-S cluster assembly factor Nubp2 homolog

1

0

High-throughput

0.232

Low

1465473

Q9VQX6
LP05054p

1

0

High-throughput

0.232

Low

1465477

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.232

Low

1465479

FRL
Formin-like protein

1

0

High-throughput

0.232

Low

1465481

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

0

High-throughput

0.232

Low

1465483

Q9VVF8
Uncharacterized protein, isoform A

1

0

High-throughput

0.232

Low

1465500

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.232

Low

1465502

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

1465504

Q9W1H8
acetyl-CoA C-acyltransferase

1

0

High-throughput

0.232

Low

1465509

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025