Interactor 1: KS6B1 (P23443)
Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
Gene: RPS6KB1

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 12150926, 12604610, 33852892, 16837165, 19402821, 25273559, 21795849, 15809305, 22493283, 21071439, 23184942, 26348909
Identification Methods affinity chromatography technology, unspecified method, enzymatic study, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT~Pkinase
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009410 - response to xenobiotic stimulus
GO:0031929 - TOR signaling
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 525
Hs

1 1335
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Last updated: 15 Jul 2024