Protein: PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-1) (Phospholipase C-eta-1) (PLC-eta-1) (Phospholipase C-like protein 3) (PLC-L3)

Gene: PLCH1
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q4KWH8

Gene Ontology (top 5):
GO:0004435 - phosphatidylinositol phospholipase C activity
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0016042 - lipid catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

350215

RASK
GTPase KRas

2

20

High-throughput

0.754

High

982076

1433F
14-3-3 protein eta

4

6

High-throughput

0.699

High

683396

1433B
14-3-3 protein beta/alpha

4

6

High-throughput

0.691

High

904644

1433G
14-3-3 protein gamma

4

7

High-throughput

0.691

High

927108

1433Z
14-3-3 protein zeta/delta

4

7

High-throughput

0.691

High

646947

1433T
14-3-3 protein theta

3

6

High-throughput

0.650

High

318150

DIRA3
GTP-binding protein Di-Ras3

1

4

High-throughput

0.618

High

348700

RASN
GTPase NRas

1

20

High-throughput

0.618

High

411745

LCK
Tyrosine-protein kinase Lck

1

17

High-throughput

0.618

High

433798

LYN
Tyrosine-protein kinase Lyn

1

17

High-throughput

0.618

High

900537

RHOA
Transforming protein RhoA

1

16

High-throughput

0.618

High

915719

RHOB
Rho-related GTP-binding protein RhoB

1

17

High-throughput

0.618

High

1070221

RAB35
Ras-related protein Rab-35

1

3

High-throughput

0.618

High

909627

1433E
14-3-3 protein epsilon

2

2

High-throughput

0.611

High

1022910

CDC16
Cell division cycle protein 16 homolog

2

0

High-throughput

0.602

High

338511

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.565

High

895108

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.553

High

1117596

DUS16
Dual specificity protein phosphatase 16

1

3

High-throughput

0.536

High

1117602

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

4

High-throughput

0.536

High

400930

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

798144

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

0

High-throughput

0.513

High

806546

RL28
Large ribosomal subunit protein eL28

1

0

High-throughput

0.513

High

1117592

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

1117600

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.513

High

1117585

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

1

High-throughput

0.489

High

279578

FLOT1
Flotillin-1

1

1

High-throughput

0.479

High

684076

1433S
14-3-3 protein sigma

1

7

High-throughput

0.479

High

716700

CTNA1
Catenin alpha-1

1

2

High-throughput

0.479

High

717136

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

818111

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

876403

AFAD
Afadin

1

4

High-throughput

0.479

High

940442

CXAR
Coxsackievirus and adenovirus receptor

1

2

High-throughput

0.479

High

1083853

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.479

High

1084026

OCLN
Occludin

1

2

High-throughput

0.479

High

1117589

PARD3
Partitioning defective 3 homolog

1

1

High-throughput

0.479

High

1117594

LZTS2
Leucine zipper putative tumor suppressor 2

1

2

High-throughput

0.479

High

1117598

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

567087

CXA1
Gap junction alpha-1 protein

1

0

High-throughput

0.458

High

1117587

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1117597

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

1117599

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1117590

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

High-throughput

0.457

High

1117595

MTA3
Metastasis-associated protein MTA3

1

1

Small-scale

0.445

High

1066987

BRD3
Bromodomain-containing protein 3

1

5

High-throughput

0.437

High

1117588

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

1

1

High-throughput

0.437

High

1117591

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

1117601

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.437

High

70154

B2CML4
Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3DE

1

1

High-throughput

0.407

High

744416

ETFB
Electron transfer flavoprotein subunit beta

2

0

High-throughput

0.328

High

1117586

CF141
Uncharacterized protein C6orf141

2

0

High-throughput

0.328

High

1101707

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1117593

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

305475

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

548815

HIS3
Histatin-3

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024