HitPredict

Interactor 1: PTPRG (P23470)
Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48)
Gene: PTPRG

Interactor 2: PTPRG (P23470)
Receptor-type tyrosine-protein phosphatase gamma (Protein-tyrosine phosphatase gamma) (R-PTP-gamma) (EC 3.1.3.48)
Gene: PTPRG

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.815

The method score is based on:

Property Details
Experiments 19167335, 15978577
Identification Methods pull down, cosedimentation in solution, comigration in sds page, tox-r dimerization assay
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Carb_anhydrase~Carb_anhydrase, fn3~fn3, Y_phosphatase~Y_phosphatase
Common GO terms GO:0004725 - protein tyrosine phosphatase activity
GO:0005001 - transmembrane receptor protein tyrosine phosphatase activity
GO:0005886 - plasma membrane
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0010633 - negative regulation of epithelial cell migration
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024