HitPredict

Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	15598710
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 166 Hs			1 247
+	Rn
		799736 COF1_RAT (1-166): 3.11e-72: 216: 99.40		1433Z_RAT (2-245): 8.46e-109: 315: 74.59
+	Hs
		618048 COF1_HUMAN (1-166): 4.46e-72: 215: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		617994 COF1_HUMAN (1-166): 4.46e-72: 215: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		904498 TWF1_HUMAN (3-157): 1.01e-34: 126: 21.52		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Mm
		935604 TWF1_MOUSE (3-157): 1.15e-33: 123: 20.89		1433F_MOUSE (1-246): 1.51e-136: 385: 86.99