HitPredict

Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: RN114 (Q9ET26)
E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313)
Gene: Rnf114

Species: Mus musculus

Source: innatedb

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21731497
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 424 Mm			1 229
+	Mm
		619049 IRF8_MOUSE (1-424): 0: 586: 100.00		TRI26_MOUSE (16-162): 7.29e-32: 123: 18.95
+	Hs
		584932 IRF8_HUMAN (1-424): 0: 574: 89.67		RO52_HUMAN (26-224): 6.31e-32: 123: 16.27
+	Mm
		618926 IRF8_MOUSE (1-424): 0: 586: 100.00		TRAF6_MOUSE (4-225): 1.08e-25: 106: 17.62
+	Hs
		971763 IRF8_HUMAN (1-424): 0: 574: 89.67		TRAF6_HUMAN (4-225): 4.45e-26: 107: 17.98
+	Mm
		880598 IRF5_MOUSE (9-422): 1.81e-165: 476: 33.04		TRAF6_MOUSE (4-225): 1.08e-25: 106: 17.62
+	Hs
		584953 IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75		RO52_HUMAN (26-224): 6.31e-32: 123: 16.27
+	Hs
		1039479 IRF5_HUMAN (9-422): 1.01e-158: 458: 30.75		TRAF6_HUMAN (4-225): 4.45e-26: 107: 17.98
+	Hs
		1071083 IRF4_HUMAN (6-384): 4.64e-155: 447: 42.27		TRAF6_HUMAN (4-225): 4.45e-26: 107: 17.98
+	Hs
		1019304 IRF3_HUMAN (9-388): 6.95e-146: 423: 28.72		TRI26_HUMAN (16-229): 5.28e-33: 126: 13.18
+	Hs
		584964 IRF3_HUMAN (9-388): 6.95e-146: 423: 28.72		RO52_HUMAN (26-224): 6.31e-32: 123: 16.27
+	Hs
		1024676 IRF3_HUMAN (9-388): 6.95e-146: 423: 28.72		TRAF3_HUMAN (24-207): 1.48e-29: 117: 19.39
+	Hs
		1056477 IRF3_HUMAN (9-388): 6.95e-146: 423: 28.72		TRAF6_HUMAN (4-225): 4.45e-26: 107: 17.98
+	Mm
		936903 IRF3_MOUSE (9-396): 7.44e-136: 397: 24.69		TRI26_MOUSE (16-162): 7.29e-32: 123: 18.95
+	Mm
		936217 IRF7_MOUSE (1-383): 5.53e-120: 358: 25.11		TRAF6_MOUSE (4-225): 1.08e-25: 106: 17.62
+	Hs
		585026 IRF7_HUMAN (12-383): 4.85e-111: 337: 21.46		RO52_HUMAN (26-224): 6.31e-32: 123: 16.27
+	Hs
		1273358 IRF7_HUMAN (12-383): 4.85e-111: 337: 21.46		TRAF6_HUMAN (4-225): 4.45e-26: 107: 17.98
+	Hs
		501044 IRF1_HUMAN (9-266): 9.31e-86: 266: 27.27		TRAF3_HUMAN (24-207): 1.48e-29: 117: 19.39
+	Hs
		501098 IRF1_HUMAN (9-266): 9.31e-86: 266: 27.27		TRAF6_HUMAN (4-225): 4.45e-26: 107: 17.98