HitPredict

Interactor 1: PSA3 (P23638)
Proteasome subunit alpha type-3 (Macropain subunit Y13) (Multicatalytic endopeptidase complex subunit Y13) (Proteasome component Y13) (Proteinase YSCE subunit 13)
Gene: PRE9

Interactor 2: PSA2 (P23639)
Proteasome subunit alpha type-2 (Macropain subunit Y7) (Multicatalytic endopeptidase complex subunit Y7) (Proteasome component Y7) (Proteinase YSCE subunit 7)
Gene: PRE8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.975

The method score is based on:

Property Details
Experiments 11595789, 11805826, 16554755, 18467557, 37968396, 16429126, 32868373, 15253422, 14759368
Identification Methods two hybrid, tandem affinity purification, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction, two hybrid array, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Proteasome~Proteasome, Proteasome~Proteasome_A_N, Proteasome_A_N~Proteasome_A_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex
GO:0034515 - proteasome storage granule
and 1 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 258
Sc

1 250
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs
+ Hs
+ Hv
+ Sp

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Last updated: 15 Jul 2024