HitPredict

Interactor 1: PSA3 (P23638)
Proteasome subunit alpha type-3 (Macropain subunit Y13) (Multicatalytic endopeptidase complex subunit Y13) (Proteasome component Y13) (Proteinase YSCE subunit 13)
Gene: PRE9

Interactor 2: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0034515 - proteasome storage granule GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Sc			1 945
+	Hs
		637988 PSA3_HUMAN (5-256): 6.88e-104: 303: 31.35		PSMD1_HUMAN (3-926): 0: 1116: 39.98
+	Hs
		637734 PSA2_HUMAN (1-243): 1.58e-102: 299: 35.39		PSMD1_HUMAN (3-926): 0: 1116: 39.98
+	Hs
		638180 PSA4_HUMAN (3-239): 2.86e-94: 279: 53.36		PSMD1_HUMAN (3-926): 0: 1116: 39.98
+	Hs
		156342 PSA7_HUMAN (6-240): 2.48e-91: 271: 35.44		PSMD1_HUMAN (3-926): 0: 1116: 39.98
+	Hs
		687 PSA3_HUMAN (5-256): 6.88e-104: 303: 31.35		A0A087WW66_HUMAN (3-926): 0: 1016: 36.69
+	Hs
		686 PSA2_HUMAN (1-243): 1.58e-102: 299: 35.39		A0A087WW66_HUMAN (3-926): 0: 1016: 36.69
+	Hs
		688 PSA4_HUMAN (3-239): 2.86e-94: 279: 53.36		A0A087WW66_HUMAN (3-926): 0: 1016: 36.69
+	Hs
		689 PSA5_HUMAN (1-242): 3.57e-91: 270: 34.41		A0A087WW66_HUMAN (3-926): 0: 1016: 36.69
+	Dm
		1278636 PSA5_DROME (1-243): 1.66e-92: 274: 32.80		PSMD1_DROME (1-927): 0: 990: 36.04
+	Dm
		574031 PSA4_DROME (3-242): 5.41e-91: 271: 50.41		PSMD1_DROME (1-927): 0: 990: 36.04
+	Hs
		637871 PSA3_HUMAN (5-256): 6.88e-104: 303: 31.35		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Hs
		637679 PSA2_HUMAN (1-243): 1.58e-102: 299: 35.39		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Hs
		638122 PSA4_HUMAN (3-239): 2.86e-94: 279: 53.36		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Hs
		156281 PSA7_HUMAN (6-240): 2.48e-91: 271: 35.44		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Hs
		656214 PSA5_HUMAN (1-242): 3.57e-91: 270: 34.41		PSMD2_HUMAN (9-770): 0: 760: 17.31
+	Dm
		1278652 PSA5_DROME (1-243): 1.66e-92: 274: 32.80		Q9VW54_DROME (13-770): 0: 651: 17.61
+	Dm
		574050 PSA4_DROME (3-242): 5.41e-91: 271: 50.41		Q9VW54_DROME (13-770): 0: 651: 17.61
+	Sp
		953201 PSA3_SCHPO (3-249): 2.33e-98: 289: 60.73		RPN1_SCHPO (9-770): 0: 621: 18.33
+	Sp
		953217 PSA5_SCHPO (1-245): 3.18e-92: 273: 33.47		RPN1_SCHPO (9-770): 0: 621: 18.33
+	Sc
		619357 PSA3_YEAST (1-258): 2.22e-96: 284: 100.00		RPN1_YEAST (9-573): 1.13e-134: 430: 17.33