Interactor 1: JUNO (A6ND01)
Sperm-egg fusion protein Juno (Folate receptor 4) (Folate receptor delta) (FR-delta) (IZUMO1 receptor protein JUNO)
Gene: IZUMO1R
Interactor 2: IZUM1 (Q8IYV9)
Izumo sperm-egg fusion protein 1 (Oocyte binding/fusion factor) (OBF) (Sperm-specific protein izumo)
Gene: IZUMO1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.70 | 0.90 | 0.798 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27309818, 27309808 |
| Identification Methods | dynamic light scattering, x-ray crystallography, molecular sieving, x ray scattering, mass spectrometry study of hydrogen/deuterium exchange, isothermal titration calorimetry, surface plasmon resonance, bio-layer interferometry, cosedimentation in solution |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Folate_rec~IZUMO, Folate_rec~Izumo-Ig |
| Common GO terms | GO:0005102 - signaling receptor binding GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007338 - single fertilization GO:0007342 - fusion of sperm to egg plasma membrane involved in single fertilization and 1 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
