HitPredict

Interactor 1: GATA2 (P23769)
Endothelial transcription factor GATA-2 (GATA-binding protein 2)
Gene: GATA2

Interactor 2: TLE3 (Q04726)
Transducin-like enhancer protein 3 (Enhancer of split groucho-like protein 3) (ESG3)
Gene: TLE3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 480 Hs			1 772
+	Hs
		620329 GATA2_HUMAN (1-480): 0: 529: 100.00		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		620331 GATA2_HUMAN (1-480): 0: 529: 100.00		TLE4_HUMAN (1-772): 9.37e-179: 533: 80.65
+	Hs
		620482 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		620481 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		620335 GATA2_HUMAN (1-480): 0: 529: 100.00		TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19
+	Hs
		554432 GATA1_HUMAN (186-480): 8.32e-69: 227: 43.35		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		980900 TRPS1_HUMAN (153-447): 1.96e-56: 204: 23.76		TLE3_HUMAN (1-772): 0: 583: 100.00
+	Hs
		554431 GATA1_HUMAN (186-480): 8.32e-69: 227: 43.35		TLE1_HUMAN (1-772): 0: 538: 77.42
+	Hs
		620487 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19
+	Hs
		620419 GATA2_HUMAN (1-480): 0: 529: 100.00		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		620569 GATA3_HUMAN (1-480): 3.1e-135: 399: 61.24		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		554438 GATA1_HUMAN (186-480): 8.32e-69: 227: 43.35		TLE5_HUMAN (1-200): 1.22e-100: 310: 62.19
+	Hs
		799000 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		TBL1R_HUMAN (571-771): 3.06e-46: 174: 15.07
+	Hs
		798837 GATA4_HUMAN (107-479): 1.15e-69: 230: 32.41		GBB2_HUMAN (688-771): 3.6e-14: 76.4: 16.47
+	Sp
		999839 FEP1_SCHPO (347-470): 1.09e-24: 108: 37.01		TUP11_SCHPO (22-606): 7.76e-53: 195: 10.78
+	Rn
		803059 GATA4_RAT (107-479): 3.62e-66: 221: 32.41		GBB2_RAT (688-771): 3.6e-14: 76.4: 16.47
+	Ce
		567433 ELT2_CAEEL (146-416): 3.71e-64: 215: 26.03		GBB1_CAEEL (657-771): 1.06e-13: 75.2: 16.67