HitPredict

Interactor 1: GATA3 (P23771)
Trans-acting T-cell-specific transcription factor GATA-3 (GATA-binding factor 3)
Gene: GATA3

Interactor 2: TRPS1 (Q9UHF7)
Zinc finger transcription factor Trps1 (Tricho-rhino-phalangeal syndrome type I protein) (Zinc finger protein GC79)
Gene: TRPS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GATA~GATA
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus and 2 others more... GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 1281
+	Hs
		620437 GATA2_HUMAN (1-443): 3.16e-135: 399: 61.24		TRPS1_HUMAN (1-1281): 0: 1888: 100.00
+	Hs
		620440 GATA2_HUMAN (1-443): 3.16e-135: 399: 61.24		IKZF3_HUMAN (850-1268): 4.38e-82: 280: 18.63
+	Hs
		620294 GATA3_HUMAN (1-443): 2.52e-176: 502: 100.00		GATA2_HUMAN (821-1072): 2.62e-27: 119: 20.60
+	Hs
		620532 GATA3_HUMAN (1-443): 2.52e-176: 502: 100.00		ZN709_HUMAN (1113-1266): 3.48e-14: 79.2: 13.55
+	Hs
		554445 GATA1_HUMAN (186-443): 1.66e-60: 204: 40.56		IKZF1_HUMAN (781-1272): 5.18e-107: 349: 19.45
+	Mm
		140175 GATA2_MOUSE (1-443): 8.13e-134: 395: 60.41		GATA2_MOUSE (821-1072): 5.46e-28: 121: 19.48
+	Mm
		994723 GATA6_MOUSE (92-430): 5.07e-82: 265: 33.71		GATA4_MOUSE (870-1060): 5.1e-45: 171: 29.00
+	Mm
		570296 GATA6_MOUSE (92-430): 5.07e-82: 265: 33.71		GATA1_MOUSE (804-1033): 5.18e-40: 155: 20.21
+	Hs
		798794 GATA4_HUMAN (134-436): 2.12e-72: 236: 38.87		GATA4_HUMAN (870-1060): 3.74e-45: 171: 28.36
+	Mm
		570281 GATA1_MOUSE (185-443): 6.07e-58: 197: 39.37		GATA1_MOUSE (804-1033): 5.18e-40: 155: 20.21
+	Sc
		641133 DAL80_YEAST (315-436): 2e-34: 131: 24.46		GZF3_YEAST (815-1216): 1.18e-46: 178: 16.71
+	Sc
		792432 GZF3_YEAST (173-313): 3.32e-12: 70.4: 26.35		GZF3_YEAST (815-1216): 1.18e-46: 178: 16.71
+	Ce
		108154 EGL18_CAEEL (317-411): 1.68e-27: 114: 31.96		ELT6_CAEEL (887-997): 4.1e-23: 104: 32.74
+	Ce
		108368 ELT6_CAEEL (308-419): 9.63e-25: 106: 30.36		EHN3_CAEEL (1128-1269): 5.94e-24: 104: 21.92
+	Sp
		1013534 FEP1_SCHPO (315-441): 1.66e-26: 113: 33.80		FEP1_SCHPO (893-1036): 3.4e-12: 72.9: 21.52