HitPredict

Interactor 1: MDM2 (P23804)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: RL23 (P62830)
Large ribosomal subunit protein uL14 (60S ribosomal protein L23)
Gene: Rpl23

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 20832751, 36435197
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression
and 2 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 489
Mm

1 140
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024