Protein: NDK3
Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3)

Gene: NDK3, NME3
Organism: Homo sapiens
Interactions: 127
UniProt ID: Q13232

Gene Ontology (top 5):
GO:0004550 - nucleoside diphosphate kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

584752

NDKA
Nucleoside diphosphate kinase A

6

17

Small-scale

0.954

High

648150

NDKB
Nucleoside diphosphate kinase B

5

17

Small-scale

0.929

High

143841

NDKM
Nucleoside diphosphate kinase, mitochondrial

3

16

High-throughput

0.861

High

248209

NDK8
Putative nucleoside diphosphate kinase

2

16

High-throughput

0.712

High

226766

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

4

3

High-throughput

0.705

High

1098770

UBQL1
Ubiquilin-1

3

2

High-throughput

0.675

High

1098765

EXD2
Exonuclease 3'-5' domain-containing protein 2

3

3

High-throughput

0.662

High

1098723

BBS7
BBSome complex member BBS7

3

0

High-throughput

0.634

High

1098750

BBS2
BBSome complex member BBS2

3

0

High-throughput

0.634

High

1098731

TTC8
Tetratricopeptide repeat protein 8

2

2

High-throughput

0.628

High

1098743

BBS4
BBSome complex member BBS4

2

1

High-throughput

0.628

High

1098717

TBA1A
Tubulin alpha-1A chain

2

5

High-throughput

0.611

High

1098768

UBQL2
Ubiquilin-2

2

2

High-throughput

0.606

High

1098708

PTHB1
Protein PTHB1

2

0

High-throughput

0.602

High

1098725

BBS5
BBSome complex member BBS5

2

0

High-throughput

0.602

High

457408

TBB5
Tubulin beta chain

2

6

High-throughput

0.601

High

1098703

TBB2A
Tubulin beta-2A chain

2

6

High-throughput

0.601

High

1098714

DESI1
Desumoylating isopeptidase 1

2

0

High-throughput

0.580

High

104720

F6XY72
nucleoside-diphosphate kinase

1

16

High-throughput

0.575

High

396033

ESR1
Estrogen receptor

2

5

High-throughput

0.571

High

1098778

MTCH2
Mitochondrial carrier homolog 2

2

4

High-throughput

0.571

High

1098738

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

3

High-throughput

0.553

High

899872

FXR1
RNA-binding protein FXR1

1

4

High-throughput

0.541

High

900307

FXR2
RNA-binding protein FXR2

1

4

High-throughput

0.541

High

1098761

UBQL4
Ubiquilin-4

1

6

High-throughput

0.541

High

507182

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

7

High-throughput

0.536

High

930301

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

3

High-throughput

0.536

High

1098709

TBB8
Tubulin beta-8 chain

1

6

High-throughput

0.536

High

1098722

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1098728

S2529
Mitochondrial basic amino acids transporter

1

2

High-throughput

0.536

High

1098732

S2540
Mitochondrial glutathione transporter SLC25A40

1

2

High-throughput

0.536

High

1098741

SFXN2
Sideroflexin-2

1

1

High-throughput

0.536

High

1098753

TBB1
Tubulin beta-1 chain

1

6

High-throughput

0.536

High

1098756

EHD1
EH domain-containing protein 1

1

1

High-throughput

0.536

High

1098758

XPO5
Exportin-5

1

1

High-throughput

0.536

High

1098771

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

3

High-throughput

0.536

High

1098777

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

1

High-throughput

0.536

High

278852

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.513

High

552001

ADT1
ADP/ATP translocase 1

1

0

High-throughput

0.513

High

848022

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.513

High

922427

CLH2
Clathrin heavy chain 2

1

0

High-throughput

0.513

High

1098707

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.513

High

1098710

UBR4
E3 ubiquitin-protein ligase UBR4

1

0

High-throughput

0.513

High

1098711

INT11
Integrator complex subunit 11

1

0

High-throughput

0.513

High

1098715

GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

1098729

MROH1
Maestro heat-like repeat-containing protein family member 1

1

0

High-throughput

0.513

High

1098730

BBS1
BBSome complex member BBS1

1

0

High-throughput

0.513

High

1098769

NRBP
Nuclear receptor-binding protein

1

0

High-throughput

0.513

High

422040

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

944228

JAM2
Junctional adhesion molecule B

1

1

High-throughput

0.494

High

166909

MGST3
Glutathione S-transferase 3, mitochondrial

1

1

High-throughput

0.479

High

293646

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.479

High

537092

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

650147

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.479

High

695358

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

768095

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

777677

VGFR3
Vascular endothelial growth factor receptor 3

1

2

High-throughput

0.479

High

787011

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

2

High-throughput

0.479

High

830668

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

934556

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

942596

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.479

High

947180

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

3

High-throughput

0.479

High

970434

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

1098705

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

1

High-throughput

0.479

High

1098706

DUS6
Dual specificity protein phosphatase 6

1

6

High-throughput

0.479

High

1098716

M3K15
Mitogen-activated protein kinase kinase kinase 15

1

2

High-throughput

0.479

High

1098736

AKAP1
A-kinase anchor protein 1, mitochondrial

1

3

High-throughput

0.479

High

1098737

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1098740

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1098745

RING2
E3 ubiquitin-protein ligase RING2

1

4

High-throughput

0.479

High

1098746

DUS9
Dual specificity protein phosphatase 9

1

6

High-throughput

0.479

High

1098748

DUS23
Dual specificity protein phosphatase 23

1

10

High-throughput

0.479

High

1098755

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1098757

SFXN1
Sideroflexin-1

1

1

High-throughput

0.479

High

1098763

DUS22
Dual specificity protein phosphatase 22

1

6

High-throughput

0.479

High

1098766

OCAD1
OCIA domain-containing protein 1

1

3

High-throughput

0.479

High

1098767

KS6B2
Ribosomal protein S6 kinase beta-2

1

2

High-throughput

0.479

High

164325

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

774324

BASI
Basigin

1

0

High-throughput

0.458

High

1098724

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

1098727

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.458

High

1098739

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.458

High

1098751

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1098752

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.458

High

1098759

PLRKT
Plasminogen receptor

1

0

High-throughput

0.458

High

1098764

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.458

High

1098774

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

1098775

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.458

High

61493

VWA8
von Willebrand factor A domain-containing protein 8

1

2

High-throughput

0.445

High

538750

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

1

High-throughput

0.445

High

653291

HEMH
Ferrochelatase, mitochondrial

1

2

High-throughput

0.445

High

1098517

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

2

High-throughput

0.445

High

1098718

TPC6B
Trafficking protein particle complex subunit 6B

1

1

High-throughput

0.445

High

1098720

TPPC5
Trafficking protein particle complex subunit 5

1

1

High-throughput

0.445

High

1098734

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

1098744

TCPQM
T-complex protein 1 subunit theta-like 2

1

5

High-throughput

0.445

High

1098754

TRABD
TraB domain-containing protein

1

2

High-throughput

0.445

High

1098760

S17A5
Sialin

1

2

High-throughput

0.445

High

1098772

TPPC4
Trafficking protein particle complex subunit 4

1

1

High-throughput

0.445

High

1098776

TPPC1
Trafficking protein particle complex subunit 1

1

1

High-throughput

0.445

High

218140

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

588601

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

1098719

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1098762

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

1098773

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

221732

TPPC3
Trafficking protein particle complex subunit 3

1

0

High-throughput

0.426

High

767087

SPB6
Serpin B6

1

0

High-throughput

0.426

High

874033

TPC10
Trafficking protein particle complex subunit 10

1

0

High-throughput

0.426

High

1098712

LYPL1
Lysophospholipase-like protein 1

1

0

High-throughput

0.426

High

1098742

TPPC9
Trafficking protein particle complex subunit 9

1

0

High-throughput

0.426

High

1098747

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.426

High

1098749

IFT27
Intraflagellar transport protein 27 homolog

1

0

High-throughput

0.426

High

701455

5HT2A
5-hydroxytryptamine receptor 2A

1

1

Small-scale

0.417

High

189318

NMDE4
Glutamate receptor ionotropic, NMDA 2D

1

2

High-throughput

0.407

High

1088764

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

2

High-throughput

0.407

High

1098726

CTL3
Choline transporter-like protein 3

1

2

High-throughput

0.407

High

1098713

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

459281

CATL1
Procathepsin L

1

0

High-throughput

0.249

Low

847515

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

1098721

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.249

Low

848480

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.232

Low

912670

CTR2
Cationic amino acid transporter 2

1

0

High-throughput

0.232

Low

994911

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.232

Low

1097246

S13A2
Solute carrier family 13 member 2

1

0

High-throughput

0.232

Low

1098704

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.232

Low

1098733

TPC14
Trafficking protein particle complex subunit 14

1

0

High-throughput

0.232

Low

1098735

SELM
Selenoprotein M

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025