HitPredict

Interactor 1: PHOP (P23836)
Transcriptional regulatory protein PhoP
Gene: PHOP

Interactor 2: PHOQ (P23837)
Sensor protein PhoQ (EC 2.7.13.3) (EC 3.1.3.-) (Sensor histidine protein kinase/phosphatase PhoQ)
Gene: PHOQ

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.696

Property	Details
Experiments	16176121, 15522865
Identification Methods	phosphotransferase assay, affinity chromatography technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HATPase_c~Response_reg
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 223 Ec			1 486
+	Ec
		467568 CUSR_ECOLI (1-222): 5.65e-72: 220: 32.74		CUSS_ECOLI (119-477): 3.52e-70: 233: 18.93
+	Mx
		1091479 Q1DCL7_MYXXD (3-221): 8.75e-76: 230: 28.13		Q1D333_MYXXD (176-484): 9.66e-64: 215: 17.38
+	Ec
		439475 PHOB_ECOLI (2-223): 1.94e-80: 241: 32.89		PHOR_ECOLI (211-486): 6.26e-58: 199: 21.33
+	Mx
		1091444 Q1D1K9_MYXXD (2-223): 2.72e-72: 220: 30.05		Q1D333_MYXXD (176-484): 9.66e-64: 215: 17.38
+	Mx
		1091475 Q1D8M8_MYXXD (3-222): 2.36e-71: 218: 31.98		Q1D333_MYXXD (176-484): 9.66e-64: 215: 17.38
+	Mx
		1091248 Q1D1K9_MYXXD (2-223): 2.72e-72: 220: 30.05		Q1CVV2_MYXXD (237-483): 1.2e-59: 211: 20.46
+	Ss
		1122361 Q55942_SYNY3 (1-221): 7.11e-75: 227: 32.14		Q55941_SYNY3 (118-482): 3.46e-58: 200: 18.44
+	Ss
		937545 P72948_SYNY3 (2-221): 2.19e-74: 226: 30.87		Q55475_SYNY3 (193-478): 3.32e-59: 201: 20.46
+	Mx
		1091457 Q1D8M8_MYXXD (3-222): 2.36e-71: 218: 31.98		Q1D1W0_MYXXD (176-481): 1.5e-60: 208: 23.15
+	Ec
		465607 OMPR_ECOLI (2-220): 1.24e-70: 217: 33.04		ENVZ_ECOLI (191-477): 2.42e-60: 206: 19.31
+	Ec
		676783 BAER_ECOLI (2-222): 1.84e-69: 214: 31.70		BAES_ECOLI (69-480): 7.04e-61: 208: 16.52
+	Mx
		1091452 Q1D4T4_MYXXD (3-222): 1.21e-68: 211: 32.90		Q1D1W0_MYXXD (176-481): 1.5e-60: 208: 23.15
+	Mx
		1091453 Q1D6S6_MYXXD (1-223): 4.27e-68: 210: 33.93		Q1D1W0_MYXXD (176-481): 1.5e-60: 208: 23.15
+	Ec
		439404 CREB_ECOLI (3-221): 4.56e-69: 212: 33.78		CREC_ECOLI (127-476): 5.39e-60: 206: 20.45
+	Mx
		1091438 Q1D6S6_MYXXD (1-223): 4.27e-68: 210: 33.93		Q1D1K8_MYXXD (201-486): 1.8e-59: 204: 23.83
+	Cv
		1308005 Q9ABD5_CAUVC (3-222): 4.5e-76: 230: 34.53		Q9ABD9_CAUVC (259-481): 8.59e-43: 159: 18.56
+	Ss
		1122356 RPPA_SYNY3 (1-222): 7.55e-72: 220: 35.78		RPPB_SYNY3 (271-477): 1.39e-44: 164: 25.11
+	Mx
		1091500 Q1D4T4_MYXXD (3-222): 1.21e-68: 211: 32.90		Q1D8M1_MYXXD (270-478): 4.5e-45: 171: 21.36
+	Mx
		1091534 Q1D8M8_MYXXD (3-222): 2.36e-71: 218: 31.98		Q1D6S5_MYXXD (213-477): 1.49e-43: 161: 21.32
+	Ec
		940183 HPRR_ECOLI (1-222): 1.7e-71: 218: 28.38		HPRS_ECOLI (171-480): 1.51e-42: 158: 20.87