HitPredict

Interactor 1: CDKA1 (P24100)
Cyclin-dependent kinase A-1 (CDKA;1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog A) (CDC2aAt)
Gene: CDKA-1

Interactor 2: CCA31 (Q9FMH5)
Putative cyclin-A3-1 (G2/mitotic-specific cyclin-A3-1) (CycA3;1)
Gene: CYCA3-1

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	20407024, 20706207
Identification Methods	protein complementation assay, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms	GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 294 At			1 355
+	At
		621689 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCA32_ARATH (3-355): 2.31e-122: 358: 70.62
+	At
		621664 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCA34_ARATH (4-355): 1.37e-117: 346: 66.58
+	At
		621690 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCA11_ARATH (2-352): 2.78e-115: 343: 41.13
+	Hs
		625350 CDK2_HUMAN (1-293): 6.46e-149: 420: 67.92		CCNA1_HUMAN (7-348): 1.77e-108: 326: 35.06
+	At
		621691 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCA24_ARATH (16-350): 3.21e-111: 333: 46.45
+	At
		621660 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCA23_ARATH (6-350): 9.05e-110: 329: 44.19
+	At
		621662 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCA21_ARATH (5-349): 2.43e-109: 328: 40.58
+	At
		621653 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCA22_ARATH (3-350): 1.03e-107: 323: 40.00
+	Hs
		538471 CDK2_HUMAN (1-293): 6.46e-149: 420: 67.92		CCNB1_HUMAN (33-353): 3.03e-102: 309: 35.19
+	At
		48929 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCA33_ARATH (73-353): 9.03e-107: 317: 71.38
+	Hs
		590125 CDK2_HUMAN (1-293): 6.46e-149: 420: 67.92		CCNA2_HUMAN (5-347): 4.47e-101: 306: 33.52
+	Hs
		538521 CDK3_HUMAN (1-294): 1.39e-146: 415: 68.03		CCNB1_HUMAN (33-353): 3.03e-102: 309: 35.19
+	Mm
		956329 CDK2_MOUSE (1-293): 8.12e-140: 399: 58.36		CCNA1_MOUSE (4-348): 5.36e-108: 323: 35.33
+	Hs
		590162 CDK3_HUMAN (1-294): 1.39e-146: 415: 68.03		CCNA2_HUMAN (5-347): 4.47e-101: 306: 33.52
+	Hs
		303829 CDK2_HUMAN (1-293): 6.46e-149: 420: 67.92		CCNB2_HUMAN (1-353): 1.83e-98: 298: 30.14
+	Mm
		851183 CDK2_MOUSE (1-293): 8.12e-140: 399: 58.36		CCNA2_MOUSE (3-347): 2.71e-104: 314: 33.24
+	At
		621704 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCB23_ARATH (4-345): 4.26e-99: 301: 26.82
+	At
		621661 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCB12_ARATH (11-348): 2.04e-97: 297: 32.65
+	At
		621643 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCB11_ARATH (4-347): 5.38e-91: 280: 29.38
+	At
		621721 CDKA1_ARATH (1-294): 6.8e-145: 410: 100.00		CCB31_ARATH (5-347): 1.49e-84: 263: 27.54