Interactor 1: MCM3 (P24279)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (Minichromosome maintenance protein 3)
Gene: MCM3

Interactor 2: SLD5 (Q03406)
DNA replication complex GINS protein SLD5
Gene: SLD5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 25659432, 21362622, 21868389, 25342810, 23499444, 26255844, 16531994, 25313033, 28355556, 28815832, 31509741, 30104407, 32804080, 32075754, 37968396, 22325992, 23499531, 19661920
Identification Methods pull down, affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~Sld5, MCM_N~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0006268 - DNA unwinding involved in DNA replication
GO:0031261 - DNA replication preinitiation complex
GO:0031298 - replication fork protection complex
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 971
Sc

1 294
+ Mm
+ Sc
+ Hs
+ Sc
+ Dm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm
+ Sc
+ Hs

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Last updated: 15 Jul 2024