HitPredict

Interactor 1: PRP22 (P24384)
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22 (EC 3.6.4.13)
Gene: PRP22

Interactor 2: PRP17 (P40968)
Pre-mRNA-processing factor 17 (Cell division control protein 40)
Gene: CDC40

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	29146870, 20089683
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000350 - generation of catalytic spliceosome for second transesterification step GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1145 Sc			1 455
+	Sp
		193834 PRP22_SCHPO (1-1138): 0: 918: 44.27		PRP17_SCHPO (38-455): 5.04e-93: 293: 36.94
+	Hs
		1055447 DHX8_HUMAN (1-1137): 0: 949: 40.81		SNR40_HUMAN (30-319): 2.71e-65: 215: 14.43
+	Hs
		236220 DHX8_HUMAN (1-1137): 0: 949: 40.81		PRP17_HUMAN (4-364): 8.13e-57: 199: 12.21
+	Sc
		589433 PRP2_YEAST (252-1113): 0: 837: 34.18		PRP17_YEAST (1-455): 5.68e-97: 300: 100.00
+	Zm
		18259 A0A1D6H4I5_MAIZE (111-1135): 0: 920: 44.77		A0A1D6J4G2_MAIZE (19-323): 1.3e-63: 216: 14.33
+	Sp
		195186 PRP16_SCHPO (3-1145): 0: 819: 34.14		PRP17_SCHPO (38-455): 5.04e-93: 293: 36.94
+	Sp
		195179 CDC28_SCHPO (4-1113): 0: 762: 32.50		PRP17_SCHPO (38-455): 5.04e-93: 293: 36.94
+	Hs
		224824 DHX16_HUMAN (242-1114): 0: 780: 41.22		FBXW7_HUMAN (97-450): 1.84e-81: 267: 15.04
+	Hs
		1268324 PRP16_HUMAN (105-1139): 0: 809: 35.69		SNR40_HUMAN (30-319): 2.71e-65: 215: 14.43
+	Sp
		194920 DHX15_SCHPO (410-1129): 0: 716: 44.82		PRP17_SCHPO (38-455): 5.04e-93: 293: 36.94
+	Hs
		195393 DHX15_HUMAN (471-1112): 0: 746: 47.10		WDR5_HUMAN (195-455): 5.35e-79: 250: 14.45
+	Hs
		224827 DHX16_HUMAN (242-1114): 0: 780: 41.22		SNR40_HUMAN (30-319): 2.71e-65: 215: 14.43
+	Sc
		554227 PRP16_YEAST (217-1109): 0: 670: 35.31		PRP17_YEAST (1-455): 5.68e-97: 300: 100.00
+	Hs
		994278 DHX9_HUMAN (109-1144): 0: 683: 20.04		FBXW7_HUMAN (97-450): 1.84e-81: 267: 15.04
+	Hs
		903167 DHX9_HUMAN (109-1144): 0: 683: 20.04		WDR5_HUMAN (195-455): 5.35e-79: 250: 14.45
+	Sc
		630874 PRP43_YEAST (416-1106): 0: 700: 45.80		NLE1_YEAST (189-455): 4.85e-62: 211: 14.70
+	Hs
		1288306 DHX35_HUMAN (437-1114): 0: 691: 45.10		SNR40_HUMAN (30-319): 2.71e-65: 215: 14.43