Interactor 1: CCND1 (P24385)
G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)
Gene: CCND1
Interactor 2: CDN1B (P46527)
Cyclin-dependent kinase inhibitor 1B (Cyclin-dependent kinase inhibitor p27) (p27Kip1)
Gene: CDKN1B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11360184, 33854239, 34591612, 9311993, 11940657, 25416956, 26496610, 19767775, 28514442, 21654808, 16431923, 33961781, 15695403, 8978686, 19556892, 12036906, 17053782, 17254966, 34591642, 9106657 |
| Identification Methods | pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CDI~Cyclin_N |
| Common GO terms | GO:0000082 - G1/S transition of mitotic cell cycle GO:0001934 - positive regulation of protein phosphorylation GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
