HitPredict

Interactor 1: CCND1 (P24385)
G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)
Gene: CCND1

Interactor 2: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	17205132, 17081987, 18650423, 9736735
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 295 Hs			1 776
+	Hs
		943787 CCNA1_HUMAN (7-281): 7.64e-89: 274: 23.91		CUL1_HUMAN (1-776): 0: 911: 100.00
+	Hs
		590180 CCNA2_HUMAN (3-286): 6.9e-81: 252: 24.48		CUL1_HUMAN (1-776): 0: 911: 100.00
+	Hs
		538541 CCNB1_HUMAN (5-282): 3.94e-89: 273: 20.64		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Sc
		624752 CG23_YEAST (21-247): 1.9e-78: 246: 23.79		CDC53_YEAST (13-776): 0: 628: 31.36
+	Hs
		624589 CCNE1_HUMAN (25-208): 7.3e-18: 84.7: 28.50		CUL4B_HUMAN (7-776): 0: 773: 29.90
+	Dm
		872345 CCNE_DROME (54-156): 3.86e-17: 83.6: 39.42		CUL1_DROME (4-776): 0: 770: 61.98
+	Hs
		624588 CCNE1_HUMAN (25-208): 7.3e-18: 84.7: 28.50		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Dm
		872347 CCNE_DROME (54-156): 3.86e-17: 83.6: 39.42		Q5BI50_DROME (7-776): 0: 742: 29.27