Protein: ELK1
ETS domain-containing protein Elk-1

Gene: ELK1
Organism: Homo sapiens
Interactions: 110
UniProt ID: P19419

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

622411

MK01
Mitogen-activated protein kinase 1

19

19

Small-scale

0.766

High

622407

ELK1
ETS domain-containing protein Elk-1

2

18

Small-scale

0.754

High

622409

MK03
Mitogen-activated protein kinase 3

8

19

Small-scale

0.752

High

622420

MK08
Mitogen-activated protein kinase 8

4

20

Small-scale

0.701

High

133082

FOXE1
Forkhead box protein E1

1

14

Small-scale

0.700

High

622432

UBC9
SUMO-conjugating enzyme UBC9

3

8

Small-scale

0.696

High

622421

MK09
Mitogen-activated protein kinase 9

3

20

Small-scale

0.674

High

421474

A4
Amyloid-beta precursor protein

3

12

High-throughput

0.660

High

622431

SUMO1
Small ubiquitin-related modifier 1

3

3

Small-scale

0.656

High

549281

SRF
Serum response factor

3

6

Small-scale

0.651

High

622439

FLI1
Friend leukemia integration 1 transcription factor

1

19

Small-scale

0.647

High

622484

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

2

0

Small-scale

0.620

High

622466

FBX25
F-box only protein 25

2

0

Small-scale

0.598

High

622422

CRK
Adapter molecule crk

2

9

High-throughput

0.594

High

622453

NF2L2
Nuclear factor erythroid 2-related factor 2

1

20

Small-scale

0.592

High

407975

TBB4A
Tubulin beta-4A chain

2

7

High-throughput

0.571

High

415341

HSPB1
Heat shock protein beta-1

2

4

High-throughput

0.571

High

424762

ADT2
ADP/ATP translocase 2

2

2

High-throughput

0.571

High

457219

TBB5
Tubulin beta chain

2

7

High-throughput

0.571

High

534613

BIP
Endoplasmic reticulum chaperone BiP

2

7

High-throughput

0.571

High

536472

HSP7C
Heat shock cognate 71 kDa protein

2

5

High-throughput

0.571

High

552118

ADT3
ADP/ATP translocase 3

2

2

High-throughput

0.571

High

600727

HSP76
Heat shock 70 kDa protein 6

2

5

High-throughput

0.571

High

622410

PYR1
Multifunctional protein CAD

2

1

High-throughput

0.571

High

622413

AL1B1
Aldehyde dehydrogenase X, mitochondrial

2

1

High-throughput

0.571

High

622414

DNJA1
DnaJ homolog subfamily A member 1

2

5

High-throughput

0.571

High

622415

CTNB1
Catenin beta-1

2

5

High-throughput

0.571

High

622428

TXTP
Tricarboxylate transport protein, mitochondrial

2

4

High-throughput

0.571

High

622434

TBB4B
Tubulin beta-4B chain

2

7

High-throughput

0.571

High

622435

PRKDC
DNA-dependent protein kinase catalytic subunit

2

7

High-throughput

0.571

High

622436

TFAM
Transcription factor A, mitochondrial

2

20

High-throughput

0.571

High

622443

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

2

6

High-throughput

0.571

High

622446

PP2BA
Protein phosphatase 3 catalytic subunit alpha

2

2

High-throughput

0.571

High

622449

TBB2A
Tubulin beta-2A chain

2

7

High-throughput

0.571

High

622451

FAT1
Protocadherin Fat 1

2

1

High-throughput

0.571

High

622457

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

2

1

High-throughput

0.571

High

622458

ZNG1F
Zinc-regulated GTPase metalloprotein activator 1F

2

6

High-throughput

0.571

High

622462

ZNG1E
Zinc-regulated GTPase metalloprotein activator 1E

2

6

High-throughput

0.571

High

622465

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

2

6

High-throughput

0.571

High

622470

HS105
Heat shock protein 105 kDa

2

6

High-throughput

0.571

High

622475

TBA1C
Tubulin alpha-1C chain

2

6

High-throughput

0.571

High

622476

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

2

6

High-throughput

0.571

High

622477

TBB6
Tubulin beta-6 chain

2

7

High-throughput

0.571

High

622478

FACD2
Fanconi anemia group D2 protein

2

1

High-throughput

0.571

High

622480

GRPE1
GrpE protein homolog 1, mitochondrial

2

6

High-throughput

0.571

High

622483

DIC
Mitochondrial dicarboxylate carrier

2

5

High-throughput

0.571

High

622447

EP300
Histone acetyltransferase p300

1

20

Small-scale

0.561

High

622464

U17L2
Ubiquitin carboxyl-terminal hydrolase 17

1

5

Small-scale

0.561

High

622429

MK10
Mitogen-activated protein kinase 10

1

20

Small-scale

0.550

High

622438

CDK6
Cyclin-dependent kinase 6

1

1

Small-scale

0.550

High

143552

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

2

0

High-throughput

0.547

High

255568

DPM1
Dolichol-phosphate mannosyltransferase subunit 1

2

0

High-throughput

0.547

High

277888

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.547

High

346843

BAG2
BAG family molecular chaperone regulator 2

2

0

High-throughput

0.547

High

611638

ERCC2
General transcription and DNA repair factor IIH helicase subunit XPD

2

0

High-throughput

0.547

High

622424

EMD
Emerin

2

0

High-throughput

0.547

High

622425

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

2

0

High-throughput

0.547

High

622469

S39A7
Zinc transporter SLC39A7

2

0

High-throughput

0.547

High

622473

MMS19
MMS19 nucleotide excision repair protein homolog

2

0

High-throughput

0.547

High

622485

ACSL5
Long-chain-fatty-acid--CoA ligase 5

2

0

High-throughput

0.547

High

622487

HIG1A
HIG1 domain family member 1A, mitochondrial

2

0

High-throughput

0.547

High

622489

TELO2
Telomere length regulation protein TEL2 homolog

2

0

High-throughput

0.547

High

622444

EMX1
Homeobox protein EMX1

1

20

High-throughput

0.541

High

622472

HXB13
Homeobox protein Hox-B13

1

16

High-throughput

0.541

High

258757

DNJA2
DnaJ homolog subfamily A member 2

2

5

High-throughput

0.521

High

622408

CADH3
Cadherin-3

2

3

High-throughput

0.521

High

622417

HSPA9
Stress-70 protein, mitochondrial

2

9

High-throughput

0.521

High

622433

TBA1B
Tubulin alpha-1B chain

2

6

High-throughput

0.521

High

622437

S25A3
Solute carrier family 25 member 3

2

3

High-throughput

0.521

High

622442

BDH
D-beta-hydroxybutyrate dehydrogenase, mitochondrial

2

1

High-throughput

0.521

High

622450

RCN2
Reticulocalbin-2

2

3

High-throughput

0.521

High

622456

TBB8
Tubulin beta-8 chain

2

7

High-throughput

0.521

High

622460

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

2

2

High-throughput

0.521

High

622479

GHC1
Mitochondrial glutamate carrier 1

2

4

High-throughput

0.521

High

622416

SYUA
Alpha-synuclein

1

1

Small-scale

0.515

High

622445

FMR1
Fragile X messenger ribonucleoprotein 1

1

3

High-throughput

0.515

High

291751

STK16
Serine/threonine-protein kinase 16

1

1

Small-scale

0.501

High

622441

EWS
RNA-binding protein EWS

1

7

Small-scale

0.501

High

622448

HDAC1
Histone deacetylase 1

1

9

Small-scale

0.501

High

622471

CBP
CREB-binding protein

1

20

Small-scale

0.501

High

216878

KLF4
Krueppel-like factor 4

1

20

Small-scale

0.479

High

622426

CDK9
Cyclin-dependent kinase 9

1

19

Small-scale

0.479

High

622452

SYUB
Beta-synuclein

1

1

Small-scale

0.479

High

622454

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.479

High

622455

HIF1A
Hypoxia-inducible factor 1-alpha

1

17

Small-scale

0.479

High

622474

EPAS1
Endothelial PAS domain-containing protein 1

1

17

Small-scale

0.479

High

622481

TLR9
Toll-like receptor 9

1

3

Small-scale

0.479

High

622486

PADI4
Protein-arginine deiminase type-4

1

0

Small-scale

0.458

High

622423

HSP77
Putative heat shock 70 kDa protein 7

1

6

High-throughput

0.445

High

622461

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

6

High-throughput

0.445

High

622468

DOK4
Docking protein 4

1

2

Small-scale

0.437

High

599265

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

2

0

High-throughput

0.310

High

163538

TPP1
Tripeptidyl-peptidase 1

2

0

High-throughput

0.298

High

184802

SPTC1
Serine palmitoyltransferase 1

2

0

High-throughput

0.298

High

190193

MOT4
Monocarboxylate transporter 4

2

0

High-throughput

0.298

High

254269

ICMT
Protein-S-isoprenylcysteine O-methyltransferase

2

0

High-throughput

0.298

High

622412

GRN
Progranulin

2

0

High-throughput

0.298

High

622418

ARL1
ADP-ribosylation factor-like protein 1

2

0

High-throughput

0.298

High

622419

SSRA
Translocon-associated protein subunit alpha

2

0

High-throughput

0.298

High

622427

SSRD
Translocon-associated protein subunit delta

2

0

High-throughput

0.298

High

622430

TMM33
Transmembrane protein 33

2

0

High-throughput

0.298

High

622440

LAT1
Large neutral amino acids transporter small subunit 1

2

0

High-throughput

0.298

High

622459

PHLA2
Pleckstrin homology-like domain family A member 2

2

0

High-throughput

0.298

High

622463

NU188
Nucleoporin NUP188

2

0

High-throughput

0.298

High

622467

SPP
Signal peptide peptidase

2

0

High-throughput

0.298

High

622482

T161A
Transmembrane protein 161A

2

0

High-throughput

0.298

High

622490

CEPT1
Choline/ethanolaminephosphotransferase 1

2

0

High-throughput

0.298

High

344454

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.282

High

622488

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025