HitPredict

Interactor 1: RAE1 (P24386)
Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein)
Gene: CHM

Interactor 2: RB27A (P51159)
Ras-related protein Rab-27A (Rab-27) (EC 3.6.5.2) (GTP-binding protein Ram)
Gene: RAB27A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 221
+	Hs
		622577 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB1A_HUMAN (1-220): 3.18e-84: 250: 34.69
+	Hs
		622619 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB1B_HUMAN (3-219): 1.3e-83: 248: 35.02
+	Hs
		119850 RAE1_HUMAN (1-653): 0: 996: 100.00		RB27B_HUMAN (1-221): 6.03e-81: 242: 71.04
+	Hs
		622574 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB14_HUMAN (2-221): 6.59e-80: 239: 31.39
+	Hs
		622576 RAE1_HUMAN (1-653): 0: 996: 100.00		RB11A_HUMAN (3-219): 9.56e-80: 239: 34.55
+	Hs
		622590 RAE1_HUMAN (1-653): 0: 996: 100.00		RB11B_HUMAN (3-219): 1.64e-79: 239: 33.78
+	Hs
		642713 RAE2_HUMAN (1-650): 0: 938: 71.98		RB27A_HUMAN (1-221): 3.16e-85: 253: 100.00
+	Hs
		642723 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB1A_HUMAN (1-220): 3.18e-84: 250: 34.69
+	Hs
		119851 RAE2_HUMAN (1-650): 0: 938: 71.98		RB27B_HUMAN (1-221): 6.03e-81: 242: 71.04
+	Hs
		642721 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB14_HUMAN (2-221): 6.59e-80: 239: 31.39
+	Hs
		642722 RAE2_HUMAN (1-650): 0: 938: 71.98		RB11A_HUMAN (3-219): 9.56e-80: 239: 34.55
+	Hs
		642730 RAE2_HUMAN (1-650): 0: 938: 71.98		RB11B_HUMAN (3-219): 1.64e-79: 239: 33.78
+	Hs
		591450 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB3A_HUMAN (2-219): 6.29e-56: 179: 41.74
+	Hs
		622570 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB8A_HUMAN (6-187): 1.3e-52: 170: 46.70
+	Hs
		622608 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB8B_HUMAN (6-192): 2.08e-52: 169: 44.39
+	Hs
		622573 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB10_HUMAN (1-184): 9.74e-50: 162: 43.48
+	Hs
		591451 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB3A_HUMAN (2-219): 6.29e-56: 179: 41.74
+	Hs
		591507 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB3B_HUMAN (2-190): 3.75e-55: 177: 44.97
+	Hs
		642718 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB8A_HUMAN (6-187): 1.3e-52: 170: 46.70
+	Hs
		642720 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB10_HUMAN (1-184): 9.74e-50: 162: 43.48