HitPredict

Interactor 1: RAE1 (P24386)
Rab proteins geranylgeranyltransferase component A 1 (Choroideremia protein) (Rab escort protein 1) (REP-1) (TCD protein)
Gene: CHM

Interactor 2: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	8294464, 28514442, 33961781
Identification Methods	enzymatic study, pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 653 Hs			1 205
+	Hs
		622608 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		622619 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		622576 RAE1_HUMAN (1-653): 0: 996: 100.00		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		622590 RAE1_HUMAN (1-653): 0: 996: 100.00		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		622570 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		622574 RAE1_HUMAN (1-653): 0: 996: 100.00		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Hs
		642723 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		642738 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		642743 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		642722 RAE2_HUMAN (1-650): 0: 938: 71.98		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		642730 RAE2_HUMAN (1-650): 0: 938: 71.98		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		642718 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		642721 RAE2_HUMAN (1-650): 0: 938: 71.98		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Hs
		678344 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		678381 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		678394 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		678343 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		678359 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		678336 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		678341 GDIA_HUMAN (218-545): 3.76e-145: 431: 22.99		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86