HitPredict

Interactor 1: AKAP5 (P24588)
A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 79 kDa) (AKAP 79) (H21) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein)
Gene: AKAP5

Interactor 2: TRPV1 (Q8NER1)
Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)
Gene: TRPV1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	18701070
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005516 - calmodulin binding GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 839
+	Hs
		623557 AKAP5_HUMAN (1-427): 0: 545: 100.00		TRPV4_HUMAN (4-818): 8.37e-169: 512: 43.55
+	Hs
		623560 AKAP5_HUMAN (1-427): 0: 545: 100.00		TRPV2_HUMAN (27-775): 4.25e-162: 492: 44.34
+	Hs
		623548 AKAP5_HUMAN (1-427): 0: 545: 100.00		TRPV3_HUMAN (1-800): 2.34e-140: 436: 38.28
+	Mm
		88322 AKAP5_MOUSE (278-427): 5.49e-42: 159: 69.28		TRPV1_MOUSE (1-839): 0: 667: 86.67
+	Rn
		94058 F1LPP6_RAT (278-427): 8.95e-43: 161: 68.63		TRPV1_RAT (1-839): 0: 648: 85.36
+	Hs
		274703 AKAP5_HUMAN (1-427): 0: 545: 100.00		TRPA1_HUMAN (159-451): 7.89e-25: 113: 11.60