HitPredict

Interactor 1: MLE (P24785)
Dosage compensation regulator mle (EC 3.6.4.13) (Protein male-less) (Protein maleless) (Protein no action potential)
Gene: MLE

Interactor 2: MLE (P24785)
Dosage compensation regulator mle (EC 3.6.4.13) (Protein male-less) (Protein maleless) (Protein no action potential)
Gene: MLE

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 9736618, 18086708
Identification Methods two hybrid, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~HA2, DEAD~Helicase_C, dsrm~dsrm, Helicase_C~dsrm, HA2~Helicase_C, HA2~OB_NTP_bind, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind, OB_NTP_bind~OB_NTP_bind
Common GO terms GO:0000228 - nuclear chromosome
GO:0000785 - chromatin
GO:0000805 - X chromosome
GO:0001069 - regulatory region RNA binding
GO:0003678 - DNA helicase activity
and 32 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1293
Dm

1 1293
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce
+ Ce
+ Sc
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024