Protein: AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL-6-interacting protein 1) (Aip-1) (Apoptotic regulator in the membrane of the endoplasmic reticulum)

Gene: AR6P1, ARL6IP1
Organism: Homo sapiens
Interactions: 199
UniProt ID: Q15041

Gene Ontology (top 5):
GO:0002038 - positive regulation of L-glutamate import across plasma membrane
GO:0005783 - endoplasmic reticulum
GO:0005784 - Sec61 translocon complex
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1065328

RTN4
Reticulon-4

5

2

High-throughput

0.721

High

1065265

RETR3
Reticulophagy regulator 3

4

2

High-throughput

0.705

High

1065354

CERT
Ceramide transfer protein

5

0

High-throughput

0.691

High

1065330

DBLOH
Diablo IAP-binding mitochondrial protein

4

0

High-throughput

0.675

High

1065355

SNX11
Sorting nexin-11

3

7

High-throughput

0.675

High

1065356

SNX10
Sorting nexin-10

3

8

High-throughput

0.675

High

1065306

INP5K
Inositol polyphosphate 5-phosphatase K

4

0

High-throughput

0.671

High

827389

EFTU
Elongation factor Tu, mitochondrial

3

1

High-throughput

0.670

High

983537

DCE2
Glutamate decarboxylase 2

3

0

High-throughput

0.646

High

1065340

SPG21
Maspardin

3

0

High-throughput

0.646

High

1065347

NDRG4
Protein NDRG4

3

0

High-throughput

0.646

High

1040459

SNX1
Sorting nexin-1

2

5

High-throughput

0.640

High

1065245

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

3

0

High-throughput

0.639

High

1065343

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

4

1

High-throughput

0.633

High

1065332

SNX15
Sorting nexin-15

2

6

High-throughput

0.628

High

1065324

GORS2
Golgi reassembly-stacking protein 2

2

0

High-throughput

0.618

High

1065301

ZFY21
Zinc finger FYVE domain-containing protein 21

3

1

High-throughput

0.616

High

1065348

SNX12
Sorting nexin-12

3

7

High-throughput

0.616

High

844071

FXR2
RNA-binding protein FXR2

2

0

High-throughput

0.613

High

46646

A0A384ME17
Elongation factor Tu

2

1

High-throughput

0.611

High

240390

SNX2
Sorting nexin-2

2

5

High-throughput

0.606

High

1065264

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

2

High-throughput

0.606

High

1065291

STAR4
StAR-related lipid transfer protein 4

2

1

High-throughput

0.606

High

1065295

REEP6
Receptor expression-enhancing protein 6

2

3

High-throughput

0.606

High

1065357

SNX8
Sorting nexin-8

2

5

High-throughput

0.606

High

626514

FPR2
N-formyl peptide receptor 2

2

0

High-throughput

0.602

High

1065323

IPPK
Inositol-pentakisphosphate 2-kinase

2

0

High-throughput

0.602

High

132865

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

157572

MGST3
Glutathione S-transferase 3, mitochondrial

2

0

High-throughput

0.580

High

330079

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.580

High

873241

EMP1
Epithelial membrane protein 1

2

0

High-throughput

0.580

High

897174

TM258
Transmembrane protein 258

2

0

High-throughput

0.580

High

1065253

VMA21
Vacuolar ATPase assembly integral membrane protein VMA21

2

0

High-throughput

0.580

High

1065256

MF14B
Hippocampus abundant transcript-like protein 1

2

0

High-throughput

0.580

High

1065259

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.580

High

1065268

SHSA5
Protein shisa-5

2

0

High-throughput

0.580

High

1065275

CS018
Uncharacterized protein C19orf18

2

0

High-throughput

0.580

High

1065294

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

1065300

RNF5
E3 ubiquitin-protein ligase RNF5

2

0

High-throughput

0.580

High

1065305

YIPF4
Protein YIPF4

2

0

High-throughput

0.580

High

1065331

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1065337

TM248
Transmembrane protein 248

2

0

High-throughput

0.580

High

1065341

EHD3
EH domain-containing protein 3

2

0

High-throughput

0.580

High

234949

SNX3
Sorting nexin-3

1

7

High-throughput

0.573

High

307893

SNX4
Sorting nexin-4

1

4

High-throughput

0.573

High

1065319

GOLP3
Golgi phosphoprotein 3

1

2

High-throughput

0.573

High

1065353

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

1

High-throughput

0.573

High

1065281

GP152
Probable G-protein coupled receptor 152

2

2

High-throughput

0.553

High

1065297

WDFY2
WD repeat and FYVE domain-containing protein 2

2

2

High-throughput

0.553

High

958914

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.549

High

1065292

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.549

High

1065326

SENP2
Sentrin-specific protease 2

1

0

High-throughput

0.549

High

48357

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.536

High

277699

PRAF3
PRA1 family protein 3

1

1

High-throughput

0.536

High

307038

RTN3
Reticulon-3

1

2

High-throughput

0.536

High

725445

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.536

High

863438

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

961660

REEP5
Receptor expression-enhancing protein 5

1

3

High-throughput

0.536

High

1065274

RETR2
Reticulophagy regulator 2

1

2

High-throughput

0.536

High

1065278

ATLA2
Atlastin-2

1

3

High-throughput

0.536

High

1065304

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.536

High

1065321

REEP4
Receptor expression-enhancing protein 4

1

3

High-throughput

0.536

High

1065322

RETR1
Reticulophagy regulator 1

1

2

High-throughput

0.536

High

1065342

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.536

High

1065345

PRAF1
Prenylated Rab acceptor protein 1

1

1

High-throughput

0.536

High

740915

FDFT
Squalene synthase

1

0

High-throughput

0.518

High

1065285

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.518

High

1065271

Q8N5Z3
Sorting nexin 10

1

8

High-throughput

0.515

High

315192

CNEP1
CTD nuclear envelope phosphatase 1

1

0

High-throughput

0.513

High

497041

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

580352

TSN8
Tetraspanin-8

1

0

High-throughput

0.513

High

803917

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.513

High

847476

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.513

High

895081

RAB2A
Ras-related protein Rab-2A

1

0

High-throughput

0.513

High

1022332

TSN31
Tetraspanin-31

1

0

High-throughput

0.513

High

1065283

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.513

High

1065290

FAF2
FAS-associated factor 2

1

0

High-throughput

0.513

High

1065293

BSCL2
Seipin

1

0

High-throughput

0.513

High

1065318

GLP3L
Golgi phosphoprotein 3-like

1

2

High-throughput

0.508

High

160002

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

Small-scale

0.501

High

329105

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.486

High

729218

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

0

High-throughput

0.486

High

930222

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.481

High

1065313

ARL6
ADP-ribosylation factor-like protein 6

1

1

Small-scale

0.481

High

1065251

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.479

High

1065258

ATLA3
Atlastin-3

1

3

High-throughput

0.479

High

91278

E5KS60
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.470

High

1065255

Q5JS98
PBX homeobox 3

1

1

High-throughput

0.470

High

1065263

Q7KZS0
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.470

High

359958

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

1065309

B2L13
Bcl-2-like protein 13

1

0

Small-scale

0.460

High

386760

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

799999

VDAC2
Voltage-dependent anion-selective channel protein 2

1

0

High-throughput

0.458

High

882303

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

927064

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

1065257

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.458

High

1065269

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

1

0

High-throughput

0.458

High

1065280

TM10A
tRNA methyltransferase 10 homolog A

1

0

High-throughput

0.458

High

99789

F5H6I7
Atlastin GTPase 3

1

3

High-throughput

0.445

High

258926

RTN2
Reticulon-2

1

2

High-throughput

0.445

High

277063

STAM2
Signal transducing adapter molecule 2

1

1

High-throughput

0.445

High

310639

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

653594

CALR
Calreticulin

1

1

High-throughput

0.445

High

654349

CALX
Calnexin

1

1

High-throughput

0.445

High

833219

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.445

High

1065248

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

1065254

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

3

High-throughput

0.445

High

1065267

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

1065273

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.445

High

1065284

ATLA1
Atlastin-1

1

3

High-throughput

0.445

High

1065296

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

1065317

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.445

High

1065344

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.445

High

1065350

DHRS7
Dehydrogenase/reductase SDR family member 7

1

2

High-throughput

0.445

High

1065351

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.445

High

1065359

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

773167

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

1065320

Q9H4D1
Protein kinase

1

1

High-throughput

0.437

High

50146

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.426

High

58085

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

149634

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.426

High

199333

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

201013

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.426

High

202889

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

266157

ERLN1
Erlin-1

1

0

High-throughput

0.426

High

335422

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

432722

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

502118

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

532122

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.426

High

818939

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

822022

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

827792

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

847271

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.426

High

863229

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

902310

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.426

High

924001

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

0

High-throughput

0.426

High

945841

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

1026683

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

1058423

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

1062515

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.426

High

1065246

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

1065247

RCN1
Reticulocalbin-1

1

0

High-throughput

0.426

High

1065249

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

1065250

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.426

High

1065261

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

1065262

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.426

High

1065270

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.426

High

1065272

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.426

High

1065276

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

1065277

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.426

High

1065279

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.426

High

1065286

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.426

High

1065289

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

1065298

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1065303

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.426

High

1065307

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

1065310

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

1065312

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.426

High

1065314

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.426

High

1065316

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

1065327

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.426

High

1065333

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

1065339

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

1065358

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

1065288

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

5

0

High-throughput

0.375

High

713518

GLYM
Serine hydroxymethyltransferase, mitochondrial

2

0

High-throughput

0.337

High

966809

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.328

High

1065325

MYG1
MYG1 exonuclease

2

0

High-throughput

0.319

High

796404

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

0

High-throughput

0.316

High

1037574

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1065252

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.316

High

1065260

TMED8
Protein TMED8

2

0

High-throughput

0.316

High

1065266

MCEM1
Mast cell-expressed membrane protein 1

2

0

High-throughput

0.316

High

1065282

GP151
G-protein coupled receptor 151

2

0

High-throughput

0.316

High

1065287

MID49
Mitochondrial dynamics protein MID49

2

0

High-throughput

0.316

High

1065308

SYTM
Threonine--tRNA ligase, mitochondrial

2

0

High-throughput

0.316

High

1065329

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

1065334

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

1048016

RB33A
Ras-related protein Rab-33A

1

0

High-throughput

0.299

High

1065315

SNAB
Beta-soluble NSF attachment protein

1

0

High-throughput

0.299

High

1065352

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

High-throughput

0.299

High

876122

PAR2
Proteinase-activated receptor 2

1

0

High-throughput

0.282

High

157799

T4S5
Transmembrane 4 L6 family member 5

1

0

High-throughput

0.279

Low

571136

EGLN
Endoglin

1

0

High-throughput

0.279

Low

844529

RAB5C
Ras-related protein Rab-5C

1

0

High-throughput

0.279

Low

965673

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.279

Low

300669

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.269

Low

1065349

TR150
Thyroid hormone receptor-associated protein 3

1

0

High-throughput

0.269

Low

1065311

S13A1
Solute carrier family 13 member 1

1

0

Small-scale

0.251

Low

1065346

ZN391
Zinc finger protein 391

1

0

High-throughput

0.251

Low

940921

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1065299

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.249

Low

297748

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.232

Low

950617

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.232

Low

1065302

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

1065335

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

1065336

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low

1065338

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024