HitPredict

Interactor 1: MYL9 (P24844)
Myosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)
Gene: MYL9

Interactor 2: MYL6 (P60660)
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)
Gene: MYL6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005829 - cytosol GO:0008307 - structural constituent of muscle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 172 Hs			1 151
+	Hs
		409446 ML12A_HUMAN (15-172): 5.65e-65: 198: 94.30		MYL1_HUMAN (3-150): 1.84e-56: 176: 74.32
+	Hs
		159536 ML12B_HUMAN (1-172): 6.88e-67: 203: 93.02		MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76
+	Hs
		538639 MYL9_HUMAN (1-172): 1.16e-66: 202: 100.00		MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76
+	Hs
		159559 ML12B_HUMAN (1-172): 6.88e-67: 203: 93.02		MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00
+	Hs
		538637 ML12A_HUMAN (15-172): 5.65e-65: 198: 94.30		MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76
+	Hs
		580632 ML12A_HUMAN (15-172): 5.65e-65: 198: 94.30		MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00
+	Ce
		585992 MLR1_CAEEL (24-170): 1.34e-38: 131: 48.65		MLE_CAEEL (12-151): 6.35e-36: 123: 46.43
+	Ce
		585996 MLR2_CAEEL (24-170): 1.02e-38: 131: 48.65		MLE_CAEEL (12-151): 6.35e-36: 123: 46.43
+	Hs
		409438 CALM1_HUMAN (97-171): 5.89e-16: 72.5: 25.33		MYL1_HUMAN (3-150): 1.84e-56: 176: 74.32
+	Hs
		409439 CALM3_HUMAN (97-171): 5.89e-16: 72.5: 25.33		MYL1_HUMAN (3-150): 1.84e-56: 176: 74.32
+	Hs
		483897 CALM1_HUMAN (97-171): 5.89e-16: 72.5: 25.33		MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76
+	Hs
		483970 CALM2_HUMAN (97-171): 5.89e-16: 72.5: 25.33		MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76
+	Hs
		484054 CALM3_HUMAN (97-171): 5.89e-16: 72.5: 25.33		MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76
+	Hs
		483914 CALM1_HUMAN (97-171): 5.89e-16: 72.5: 25.33		MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00
+	Hs
		483988 CALM2_HUMAN (97-171): 5.89e-16: 72.5: 25.33		MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00
+	Hs
		484091 CALM3_HUMAN (97-171): 5.89e-16: 72.5: 25.33		MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00
+	Hs
		484049 CALM3_HUMAN (97-171): 5.89e-16: 72.5: 25.33		CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77
+	Hs
		483903 CALM1_HUMAN (97-171): 5.89e-16: 72.5: 25.33		CALL3_HUMAN (5-77): 1.25e-10: 57.9: 26.03
+	Hs
		483976 CALM2_HUMAN (97-171): 5.89e-16: 72.5: 25.33		CALL3_HUMAN (5-77): 1.25e-10: 57.9: 26.03
+	At
		989458 CDPK1_ARATH (62-172): 5.02e-14: 70.6: 20.18		CDPK1_ARATH (73-150): 1e-09: 57.5: 21.52